Microtubules are dynamic polymers of αβ-tubulin that are essential for intracellular
organization, organelle trafficking and chromosome segregation. Microtubule growth and …

This review discusses one-dimensional supramolecular polymers that form in aqueous
media. First, naturally occurring supramolecular polymers are described, in particular …

This review summarizes what is known about the biochemical and biophysical mechanisms
that initiate the assembly of actin filaments in cells. Assembly and disassembly of these …

A longstanding question in molecular biology is the extent to which the behavior of
macromolecules observed in vitro accurately reflects their behavior in vivo. A number of …

The actin cytoskeleton and associated motor proteins provide the driving forces for
establishing the astonishing morphological diversity and dynamics of mammalian cells …

ADF/cofilins are key regulators of actin dynamics during cellular motility, yet their precise
role and mechanism of action are shrouded in ambiguity. Direct observation of actin …

Formins are highly conserved proteins that have essential roles in remodelling the actin and
microtubule cytoskeletons to influence eukaryotic cell shape and behaviour. Recent work …