[HTML][HTML] FLASH radiotherapy treatment planning and models for electron beams

M Rahman, A Trigilio, G Franciosini, R Moeckli… - Radiotherapy and …, 2022 - Elsevier
The FLASH effect designates normal tissue sparing at ultra-high dose rate (UHDR,> 40
Gy/s) compared to conventional dose rate (∼ 0.1 Gy/s) irradiation while maintaining tumour …

[HTML][HTML] Back to the future: very high-energy electrons (VHEEs) and their potential application in radiation therapy

MG Ronga, M Cavallone, A Patriarca, AM Leite, P Loap… - Cancers, 2021 - mdpi.com
The development of innovative approaches that would reduce the sensitivity of healthy
tissues to irradiation while maintaining the efficacy of the treatment on the tumor is of crucial …

CERN-based experiments and Monte-Carlo studies on focused dose delivery with very high energy electron (VHEE) beams for radiotherapy applications

L Whitmore, RI Mackay, M Van Herk, P Korysko… - Scientific Reports, 2024 - nature.com
Abstract Very High Energy Electron (VHEE) beams are a promising alternative to
conventional radiotherapy due to their highly penetrating nature and their applicability as a …

Focused VHEE (very high energy electron) beams and dose delivery for radiotherapy applications

L Whitmore, RI Mackay, M Van Herk, JK Jones… - Scientific Reports, 2021 - nature.com
This paper presents the first demonstration of deeply penetrating dose delivery using
focused very high energy electron (VHEE) beams using quadrupole magnets in Monte Carlo …

FLASHlab@ PITZ: New R&D platform with unique capabilities for electron FLASH and VHEE radiation therapy and radiation biology under preparation at PITZ

F Stephan, M Gross, A Grebinyk, Z Aboulbanine… - Physica medica, 2022 - Elsevier
Abstract At the Photo Injector Test facility at DESY in Z euthen (PITZ), an R&D platform for
electron FLASH and very high energy electron radiation therapy and radiation biology is …

Deep seated tumour treatments with electrons of high energy delivered at FLASH rates: the example of prostate cancer

A Sarti, P De Maria, G Battistoni, M De Simoni… - Frontiers in …, 2021 - frontiersin.org
Different therapies are adopted for the treatment of deep seated tumours in combination or
as an alternative to surgical removal or chemotherapy: radiotherapy with photons (RT) …

Development of a novel fibre optic beam profile and dose monitor for very high energy electron radiotherapy at ultrahigh dose rates

JJ Bateman, E Buchanan, R Corsini… - Physics in Medicine …, 2024 - iopscience.iop.org
Objective. Very high energy electrons (VHEE) in the range of 50–250 MeV are of interest for
treating deep-seated tumours with FLASH radiotherapy (RT). This approach offers …

Plastic scintillator dosimetry of ultrahigh dose-rate 200 MeV electrons at CLEAR

A Hart, C Giguère, J Bateman, P Korysko… - IEEE Sensors …, 2024 - ieeexplore.ieee.org
Very-high-energy electron (VHEE) beams with energies greater than 100 MeV may be
promising candidates for FLASH radiotherapy due to their favorable dose distributions and …

[HTML][HTML] Very high-energy electron therapy as light-particle alternative to transmission proton FLASH therapy–An evaluation of dosimetric performances

TT Böhlen, JF Germond, L Desorgher, I Veres… - Radiotherapy and …, 2024 - Elsevier
Purpose Clinical translation of FLASH-radiotherapy (RT) to deep-seated tumours is still a
technological challenge. One proposed solution consists of using ultra-high dose rate …

Very high-energy electrons as radiotherapy opportunity

J Fischer, L Whitmore, C Desrosiers… - … Physical Journal Plus, 2024 - epjplus.epj.org
The use of very high-energy electrons (VHEEs) with energies in the range of 100-250 MeV
has recently garnered significant attention for use in radiotherapy. VHEE beams manifest …