Lamotrigine lipid nanoparticles for effective treatment of epilepsy: a focus on brain targeting via nasal route
PK Gangurde, N Ajitkumar B, L Kumar - Journal of Pharmaceutical …, 2019 - Springer
Background Pharmaceutical research in the field of medicine aims to improve the quality of
life of a patient. Epilepsy is a neurological disorder affecting a number of patients worldwide …
life of a patient. Epilepsy is a neurological disorder affecting a number of patients worldwide …
Lamotrigine loaded PLGA nanoparticles intended for direct nose to brain delivery in epilepsy: pharmacokinetic, pharmacodynamic and scintigraphy study
The present study aimed to investigate the brain targeting efficacy of Lamotrigine (LTG)
loaded PLGA nanoparticles (LTG-PNPs) upon intranasal administration. LTG-PNPs were …
loaded PLGA nanoparticles (LTG-PNPs) upon intranasal administration. LTG-PNPs were …
Eudragit-Based Nanosuspension of Poorly Water-Soluble Drug: Formulation and In Vitro–In Vivo Evaluation
The present study was performed to investigate potential of Eudragit RLPO-based
nanosuspension of glimepiride (Biopharmaceutical Classification System class II drug), for …
nanosuspension of glimepiride (Biopharmaceutical Classification System class II drug), for …
[HTML][HTML] Itraconazole nanosuspension for oral delivery: Formulation, characterization and in vitro comparison with marketed formulation
M Nakarani, AK Misra, JK Patel… - Daru: journal of Faculty of …, 2010 - ncbi.nlm.nih.gov
Methods Itraconazole nanosuspension was prepared by pearl milling technique using
zirconium oxide beads as a milling media, Poloxamer 407 as a stabilizer and glycerol as a …
zirconium oxide beads as a milling media, Poloxamer 407 as a stabilizer and glycerol as a …
Development of biopolymer-mediated nanocomposites using hot-melt extrusion to enhance the bio-accessibility and antioxidant capacity of kenaf seed flour
The current study was aimed to enhance the bio-accessibility and functionality of bioactive
compounds from kenaf seed flour. Hence, eight different formulations (F1–F8) of kenaf seed …
compounds from kenaf seed flour. Hence, eight different formulations (F1–F8) of kenaf seed …
Preconcentration and selective extraction of trace Hg (ii) by polymeric gC 3 N 4 nanosheet-packed SPE column
In this study, we successfully synthesized polymeric graphitic carbon nitride (g-C3N4)
nanosheets through thermal means and proposed their application in solid-phase extraction …
nanosheets through thermal means and proposed their application in solid-phase extraction …
Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation
TA Ahmed - International Journal of Nanomedicine, 2016 - Taylor & Francis
In this study, optimized freeze-dried finasteride nanoparticles (NPs) were prepared from
drug nanosuspension formulation that was developed using the bottom–up technique. The …
drug nanosuspension formulation that was developed using the bottom–up technique. The …
Optimized zein nanospheres for improved oral bioavailability of atorvastatin
Background This work focuses on the development of atorvastatin utilizing zein, a natural,
safe, and biocompatible polymer, as a nanosized formulation in order to overcome the poor …
safe, and biocompatible polymer, as a nanosized formulation in order to overcome the poor …
Quality-by-design approach for development of sustained-release multiple-unit beads of lamotrigine based on ion-cross-linked composite of pectin and okra mucilage …
The main objective of the present study was to develop a sustained release multiple-unit
beads of lamotrigine based on ionotropically cross-linked natural polysaccharides such as …
beads of lamotrigine based on ionotropically cross-linked natural polysaccharides such as …
Sorafenib tosylate-loaded nanosuspension: preparation, optimization, and in vitro cytotoxicity study against human HepG2 carcinoma cells
This study aimed to optimize nanosuspension of sorafenib tosylate (an anticancer
hydrophobic drug molecule) using a central composite design. Nanosuspension was …
hydrophobic drug molecule) using a central composite design. Nanosuspension was …