Overcoming barriers to patient adherence: the case for develo** innovative drug delivery systems
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …
socioeconomic consequences. Although the underlying reasons are generally understood …
Meta‐analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?
Aims Although debates over the efficacy of oral naltrexone and acamprosate in treating
alcohol use disorders tend to focus on their global efficacy relative to placebo or their …
alcohol use disorders tend to focus on their global efficacy relative to placebo or their …
[HTML][HTML] Technological interventions for medication adherence in adult mental health and substance use disorders: a systematic review
JM Steinkamp, N Goldblatt, JT Borodovsky… - JMIR mental …, 2019 - mental.jmir.org
Background: Medication adherence is critical to the effectiveness of psychopharmacologic
therapy. Psychiatric disorders present special adherence considerations, notably an altered …
therapy. Psychiatric disorders present special adherence considerations, notably an altered …
Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals
LF Vendruscolo, D Estey, V Goodell… - The Journal of …, 2015 - Am Soc Clin Investig
Alcoholism, or alcohol use disorder, is a major public health concern that is a considerable
risk factor for morbidity and disability; therefore, effective treatments are urgently needed …
risk factor for morbidity and disability; therefore, effective treatments are urgently needed …
Incubation of neural alcohol cue reactivity after withdrawal and its blockade by naltrexone
P Bach, G Weil, E Pompili, S Hoffmann… - Addiction …, 2020 - Wiley Online Library
During the first weeks of abstinence, alcohol craving in patients may increase or “incubate.”
We hypothesize that Naltrexone (NTX) blocks this incubation effect. Here, we compared NTX …
We hypothesize that Naltrexone (NTX) blocks this incubation effect. Here, we compared NTX …
The efficacy of acamprosate and naltrexone in the treatment of alcohol dependence, Europe versus the rest of the world: a meta‐analysis
Aims To determine the efficacy of acamprosate and naltrexone in the treatment of those who
are alcohol‐dependent in reducing lapse/relapse to alcohol consumption and treatment …
are alcohol‐dependent in reducing lapse/relapse to alcohol consumption and treatment …
Opioids and social bonding: naltrexone reduces feelings of social connection
Close social bonds are critical to a happy and fulfilled life and yet little is known, in humans,
about the neurochemical mechanisms that keep individuals feeling close and connected to …
about the neurochemical mechanisms that keep individuals feeling close and connected to …
Naltrexone: not just for opioids anymore
D Sudakin - Journal of Medical Toxicology, 2016 - Springer
Naltrexone is a semi-synthetic opioid with competitive antagonist activity at mu opioid
receptors. Its efficacy has been demonstrated in the treatment of alcohol and opioid …
receptors. Its efficacy has been demonstrated in the treatment of alcohol and opioid …
Noradrenergic targets for the treatment of alcohol use disorder
The role of norepinephrine (NE) in the development of alcohol use disorder (AUD) has been
studied over the past several decades. However, the NE system has been largely ignored …
studied over the past several decades. However, the NE system has been largely ignored …
Recommendations for the design and analysis of treatment trials for alcohol use disorders
Background Over the past 60 years, the view that “alcoholism” is a disease for which the
only acceptable goal of treatment is abstinence has given way to the recognition that alcohol …
only acceptable goal of treatment is abstinence has given way to the recognition that alcohol …