Progress in corneal wound healing

AV Ljubimov, M Saghizadeh - Progress in retinal and eye research, 2015 - Elsevier
Corneal wound healing is a complex process involving cell death, migration, proliferation,
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …

Wound-healing studies in cornea and skin: parallels, differences and opportunities

A Bukowiecki, D Hos, C Cursiefen… - International journal of …, 2017 - mdpi.com
The cornea and the skin are both organs that provide the outer barrier of the body. Both
tissues have developed intrinsic mechanisms that protect the organism from a wide range of …

[HTML][HTML] Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks

A Sorkio, L Koch, L Koivusalo, A Deiwick, S Miettinen… - Biomaterials, 2018 - Elsevier
There is a high demand for develo** methods to produce more native-like 3D corneal
structures. In the present study, we produced 3D cornea-mimicking tissues using human …

Human limbal biopsy–derived stromal stem cells prevent corneal scarring

S Basu, AJ Hertsenberg, ML Funderburgh… - Science translational …, 2014 - science.org
Conventional allograft therapy for corneal scarring is widespread and successful, but donor
tissue is not universally available, and some grafts fail owing to rejection and complications …

[HTML][HTML] Squishy matters–Corneal mechanobiology in health and disease

SM Thomasy, BC Leonard, MA Greiner… - Progress in retinal and …, 2024 - Elsevier
The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

Stem cells in the limbal stroma

JL Funderburgh, ML Funderburgh, Y Du - The ocular surface, 2016 - Elsevier
The corneal stroma contains a population of mesenchymal cells subjacent to the limbal
basement membrane with characteristics of adult stem cells. These 'niche cells' support …

Alternatives to eye bank native tissue for corneal stromal replacement

I Brunette, CJ Roberts, F Vidal… - Progress in retinal and …, 2017 - Elsevier
Corneal blindness is a major cause of blindness in the world and corneal transplantation is
the only widely accepted treatment to restore sight in these eyes. However, it is becoming …

Dental pulp stem cells: a new cellular resource for corneal stromal regeneration

FN Syed-Picard, Y Du, KL Lathrop… - Stem cells …, 2015 - academic.oup.com
Corneal blindness afflicts millions of individuals worldwide and is currently treated by
grafting with cadaveric tissues; however, there are worldwide donor tissue shortages, and …

Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications

GHF Yam, S Pi, Y Du, JS Mehta - Progress in Retinal and Eye Research, 2023 - Elsevier
The limbus is a transition from the cornea to conjunctiva and sclera. In human eyes, this thin
strip has a rich variation of tissue structures and composition, typifying a change from scleral …

Regenerative therapy for the Cornea

A Kumar, H Yun, ML Funderburgh, Y Du - Progress in retinal and eye …, 2022 - Elsevier
The cornea is the outmost layer of the eye, unique in its transparency and strength. The
cornea not only transmits the light essential for vision, also refracts light, giving focus to …