The development and clinical application of innovative optical ophthalmic imaging techniques

P Alexopoulos, C Madu, G Wollstein… - Frontiers in …, 2022 - frontiersin.org
The field of ophthalmic imaging has grown substantially over the last years. Massive
improvements in image processing and computer hardware have allowed the emergence of …

Current clinical applications of anterior segment optical coherence tomography angiography: a review

Y Wen, D Jiang, K Tang, W Chen - Graefe's Archive for Clinical and …, 2023 - Springer
Optical coherence tomography (OCT) is a revolutionary in vivo imaging technology that
presents real-time information on ocular structures. Angiography based on OCT, known as …

Iridocorneal angle imaging of a human donor eye by spectral-domain optical coherence tomography

S Luo, G Holland, R Khazaeinezhad, S Bradford… - Scientific Reports, 2023 - nature.com
Iridocorneal angle (ICA) details particularly the trabecular meshwork (TM), Schlemm's canal
(SC), and collector channels (CCs) play crucial roles in the regulation of the aqueous …

Differential roles of FOXC2 in the trabecular meshwork and Schlemm's canal in glaucomatous pathology

N Ujiie, PR Norden, R Fang, L Beckmann… - Life science …, 2023 - life-science-alliance.org
Impaired development and maintenance of Schlemm's canal (SC) are associated with
perturbed aqueous humor outflow and intraocular pressure. The angiopoietin (ANGPT)/TIE2 …

[HTML][HTML] From soma to synapse: imaging age-related rod photoreceptor changes in the mouse with visible light OCT

P Chauhan, AM Kho, VJ Srinivasan - Ophthalmology Science, 2023 - Elsevier
Purpose Although the outer nuclear layer (ONL) and outer plexiform layer (OPL) each
exhibit a complex internal organization, near-infrared OCT depicts both as monolithic bands …

Integral role for lysyl oxidase‐like‐1 in conventional outflow tissue function and behavior

G Li, H Schmitt, WM Johnson, C Lee… - The FASEB …, 2020 - Wiley Online Library
Abstract Lysyl oxidase‐like‐1 (LOXL1), a vital crosslinking enzyme in elastin fiber
maintenance, is essential for the stability and strength of elastic vessels and tissues …

Surface engineering of FLT4-targeted nanocarriers enhances cell-softening glaucoma therapy

MP Vincent, T Stack, A Vahabikashi, G Li… - … applied materials & …, 2021 - ACS Publications
Primary open-angle glaucoma is associated with elevated intraocular pressure (IOP) that
damages the optic nerve and leads to gradual vision loss. Several agents that reduce the …

Comparison of 1-year surgical outcomes of combined cataract surgery and gonioscopy-assisted transluminal trabeculotomy (GATT) versus cataract surgery and iStent …

H Hamze, AA Mohite, P Pandey, VCT Sung… - Graefe's Archive for …, 2021 - Springer
Purpose Evaluate the efficacy, safety, and complication rates of phacoemulsification cataract
surgery when combined with either gonioscopy-assisted transluminal trabeculotomy (GATT) …

Full circumferential morphological analysis of Schlemm's canal in human eyes using megahertz swept source OCT

X Yao, B Tan, Y Ho, X Liu, D Wong, J Chua… - Biomedical optics …, 2021 - opg.optica.org
We performed full circumferential imaging of the Schlemm's canal (SC) of two human eyes
using a Fourier domain mode-lock laser (FDML) based 1.66-MHz SS-OCT prototype at 1060 …

Diagnosing colorectal abnormalities using scattering coefficient maps acquired from optical coherence tomography

Y Zeng, WC Chapman Jr, Y Lin, S Li… - Journal of …, 2021 - Wiley Online Library
Optical coherence tomography (OCT) has shown potential in differentiating normal colonic
mucosa from neoplasia. In this study of 33 fresh human colon specimens, we report the first …