OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …

As current treatment options in OA are very limited, OA patients would benefit greatly from
some ability to self-manage their condition. Since diet may potentially affect OA, we …

Obesity, together with aging and injury, is among the main risk factors for osteoarthritis.
Obesity-related osteoarthritis can affect not only the weight-bearing joints, but also the …

Osteoarthritis (OA) has long been considered the unique consequence of a wear and tear
process leading to cartilage degradation. Indeed, it is true that excessive mechanical stress …

Osteoarthritis (OA) is a common chronic joint disorder with a multifactorial etiology including
genetic and environmental factors. Metabolic triggered inflammation, induced by nutrient …

Background Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult
disability. There is no cure for OA and there is no effective treatment to stop its progression …

Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …

Obesity is characterized by adipose tissue expansion and chronic low-grade inflammation.
Among the inflammatory mediators related to obesity development are the adipokines …

Osteoarthritis (OA) is a chronic joint disease characterized by cholesterol accumulation in
chondrocytes, cartilage degeneration, as well as extracellular matrix (ECM) destruction, and …

Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder
associated with mechanical stress and aging but also a 'metabolic syndrome'in which …