Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Passive and active markers of cortical excitability in epilepsy

G Ramantani, MB Westover, S Gliske, J Sarnthein… - …, 2023 - Wiley Online Library
Electroencephalography (EEG) has been the primary diagnostic tool in clinical epilepsy for
nearly a century. Its review is performed using qualitative clinical methods that have …

Normative intracranial EEG maps epileptogenic tissues in focal epilepsy

JM Bernabei, N Sinha, TC Arnold, E Conrad, I Ong… - Brain, 2022 - academic.oup.com
Planning surgery for patients with medically refractory epilepsy often requires recording
seizures using intracranial EEG. Quantitative measures derived from interictal intracranial …

Neural fragility as an EEG marker of the seizure onset zone

A Li, C Huynh, Z Fitzgerald, I Cajigas, D Brusko… - Nature …, 2021 - nature.com
Over 15 million patients with epilepsy worldwide do not respond to drugs. Successful
surgical treatment requires complete removal or disconnection of the seizure onset zone …

Source-sink connectivity: A novel interictal EEG marker for seizure localization

KM Gunnarsdottir, A Li, RJ Smith, JY Kang… - Brain, 2022 - academic.oup.com
Over 15 million epilepsy patients worldwide have drug-resistant epilepsy. Successful
surgery is a standard of care treatment but can only be achieved through complete resection …

Generalisability of epileptiform patterns across time and patients

H Karimi-Rouzbahani, A McGonigal - Scientific Reports, 2024 - nature.com
The complexity of localising the epileptogenic zone (EZ) contributes to surgical resection
failures in achieving seizure freedom. The distinct patterns of epileptiform activity during …

Disentangled representation learning in non-markovian causal systems

A Li, Y Pan, E Bareinboim - Advances in Neural Information …, 2025 - proceedings.neurips.cc
Considering various data modalities, such as images, videos, and text, humans perform
causal reasoning using high-level causal variables, as opposed to operating at the low …

A complex systems view on the current hypotheses of epilepsy pharmacoresistance

G Servilha‐Menezes, N Garcia‐Cairasco - Epilepsia Open, 2022 - Wiley Online Library
Drug‐resistant epilepsy remains to this day as a highly prevalent condition affecting around
one‐third of patients with epilepsy, despite all the research and the development of several …

Localizing the epileptogenic zone

B Frauscher - Current opinion in neurology, 2020 - journals.lww.com
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[HTML][HTML] High interictal connectivity within the resection zone is associated with favorable post-surgical outcomes in focal epilepsy patients

P Shah, JM Bernabei, LG Kini, A Ashourvan… - NeuroImage: Clinical, 2019 - Elsevier
Patients with drug-resistant focal epilepsy are often candidates for invasive surgical
therapies. In these patients, it is necessary to accurately localize seizure generators to …