Aplastic anemia
NS Young - New England Journal of Medicine, 2018 - Mass Medical Soc
Aplastic Anemia | New England Journal of Medicine Skip to main content The New England
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Regulatory T cells (Tregs) in liver fibrosis
K Wu, Q Qian, J Zhou, D Sun, Y Duan, X Zhu… - Cell death …, 2023 - nature.com
The ability of the human liver to both synthesize extracellular matrix (ECM), as well as
regulate fibrogenesis, are integral functions to maintaining homoeostasis. Chronic liver …
regulate fibrogenesis, are integral functions to maintaining homoeostasis. Chronic liver …
A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition
Triple-negative breast cancer (TNBC), a highly metastatic breast cancer subtype, has limited
treatment options. While a small number of patients attain clinical benefit with single-agent …
treatment options. While a small number of patients attain clinical benefit with single-agent …
Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells
Glioblastoma multiforme (GBM), the most aggressive brain cancer, recurs because
glioblastoma stem cells (GSCs) are resistant to all standard therapies. We showed that …
glioblastoma stem cells (GSCs) are resistant to all standard therapies. We showed that …
Combining AFM13, a bispecific CD30/CD16 antibody, with cytokine-activated blood and cord blood–derived NK cells facilitates CAR-like responses against CD30+ …
Abstract Purpose: Natural killer (NK)-cell recognition and function against NK-resistant
cancers remain substantial barriers to the broad application of NK-cell immunotherapy …
cancers remain substantial barriers to the broad application of NK-cell immunotherapy …
Advances in understanding the pathogenesis of acquired aplastic anaemia
L Luzzatto, AM Risitano - British Journal of Haematology, 2018 - Wiley Online Library
This review examines the evidence that bone marrow failure (BMF) in aplastic anaemia (AA)
is due to loss of haematopoietic stem cells (HSC s), which, in turn, is caused by deranged …
is due to loss of haematopoietic stem cells (HSC s), which, in turn, is caused by deranged …
Acquired severe aplastic anaemia: how medical therapy evolved in the 20th and 21st centuries
P Scheinberg - British Journal of Haematology, 2021 - Wiley Online Library
The progress in aplastic anaemia (AA) management is one of success. Once an obscure
entity resulting in death in most affected can now be successfully treated with either …
entity resulting in death in most affected can now be successfully treated with either …
Endogenous stimuli‐activatable nanomedicine for immune theranostics for cancer
W Wang, Y **, X Liu, F Chen, X Zheng… - Advanced Functional …, 2021 - Wiley Online Library
Cancer immunotherapy has witnessed significant advances in the past decade, however
challenges associated with immune‐related adverse effects and immunosuppressive tumor …
challenges associated with immune‐related adverse effects and immunosuppressive tumor …
Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa
Repair of tissue damaged during inflammatory processes is key to the return of local
homeostasis and restoration of epithelial integrity. Here we describe CD161+ regulatory T …
homeostasis and restoration of epithelial integrity. Here we describe CD161+ regulatory T …
Allogeneic hematopoietic stem cell transplantation in aplastic anemia: current indications and transplant strategies
Abstract Treatment options for newly diagnosed aplastic anemia (AA) patient includes
upfront allogeneic hematopoietic stem cell transplant (HSCT) or immunosuppressive …
upfront allogeneic hematopoietic stem cell transplant (HSCT) or immunosuppressive …