Curcumin (Cur) is a natural polyphenol with beneficial effect against obesity and related
metabolic disorders, but its precise mechanisms of action remain to be defined due to its …

Staphylococcal nuclease and Tudor domain containing 1 (SND1) is an evolutionarily
conserved protein present in eukaryotic cells from protozoa to mammals. SND1 has gained …

Background Dairy cows are often fed a high-concentrate diet to meet lactating demands, yet
long-term concentrate feeding induces subacute ruminal acidosis (SARA) and leads to a …

The understanding of genetic factors involved in the risk for obesity has identified genes that
are closely linked to obesity related diseases. A single gene effect versus multiple genes …

Background/Aims Emerging data links different aspects of lipid metabolism to liver
regeneration. In patients with acute liver failure (ALF), low levels of lipids may correlate with …

To study the role of inflammation in the pathophysiology of the fatty liver haemorrhagic
syndrome (FLHS), mature laying hens were treated with oestrogen (β-oestradiol-17 …

High-fat diet (HFD) feeding or leptin-deficient mice are extensively used as models
resembling features of human nonalcoholic fatty liver disease (NAFLD). The concurrence of …

Objectives Cuminaldehyde self-emulsified nanoemulsion (CuA-SEN) was prepared and
optimised to improve its oral bioavailability and antihepatotoxicity. Methods Cuminaldehyde …

Subacute ruminal acidosis (SARA) of dairy cattle is a widely occurring but not very overt
metabolic disorder thought to impair milk composition. The enzyme stearoyl-CoA desaturase …

Steatosis can sensitise the liver to various challenges and favour the development of non-
alcoholic fatty liver disease (NAFLD). In this context, fructose feeding promotes endotoxin …