Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy

P Tiwari, K Yadav, RP Shukla, S Gautam… - Journal of Controlled …, 2023 - Elsevier
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Improving cellular uptake of therapeutic entities through interaction with components of cell membrane

R Zhang, X Qin, F Kong, P Chen, G Pan - Drug Delivery, 2019 - Taylor & Francis
Efficient cellular delivery of biologically active molecules is one of the key factors that affect
the discovery and development of novel drugs. The plasma membrane is the first barrier that …

Nanocarriers for cancer-targeted drug delivery

P Kumari, B Ghosh, S Biswas - Journal of drug targeting, 2016 - Taylor & Francis
Nanoparticles as drug delivery system have received much attention in recent years,
especially for cancer treatment. In addition to improving the pharmacokinetics of the loaded …

Challenges in development of nanoparticle-based therapeutics

N Desai - The AAPS journal, 2012 - Springer
In recent years, nanotechnology has been increasingly applied to the area of drug
development. Nanoparticle-based therapeutics can confer the ability to overcome biological …

Ligand-targeted liposome design: challenges and fundamental considerations

GT Noble, JF Stefanick, JD Ashley, T Kiziltepe… - Trends in …, 2014 - cell.com
Nanomedicine, particularly liposomal drug delivery, has expanded considerably over the
past few decades, and several liposomal drugs are already providing improved clinical …

Extracellular vesicles as drug delivery systems: lessons from the liposome field

R van der Meel, MHAM Fens, P Vader… - Journal of controlled …, 2014 - Elsevier
Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)
lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell …

Bionanoparticles in cancer imaging, diagnosis, and treatment

Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Recent advances with liposomes as pharmaceutical carriers

VP Torchilin - Nature reviews Drug discovery, 2005 - nature.com
Liposomes—microscopic phospholipid bubbles with a bilayered membrane structure—have
received a lot of attention during the past 30 years as pharmaceutical carriers of great …

Nanocarriers' entry into the cell: relevance to drug delivery

H Hillaireau, P Couvreur - Cellular and molecular life sciences, 2009 - Springer
Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …