Immune checkpoint inhibitors for multiple myeloma immunotherapy

Z Liu, X Xu, H Liu, X Zhao, C Yang, R Fu - Experimental Hematology & …, 2023 - Springer
Multiple myeloma (MM) is related to immune disorders, recent studys have revealed that
immunotherapy can greatly benefit MM patients. Immune checkpoints can negatively …

VISTA immune regulatory effects in bypassing cancer immunotherapy: Updated

K Mortezaee, J Majidpoor, S Najafi - Life sciences, 2022 - Elsevier
Resistance to immune checkpoint inhibitors (ICIs) is a common predicament in cancer
immunotherapy, which requires urgent interventions. V-domain immunoglobulin suppressor …

Different expression patterns of VISTA concurrent with PD-1, Tim-3, and TIGIT on T cell subsets in peripheral blood and bone marrow from patients with multiple …

S Huang, Y Zhao, P Liao, J Wang, Z Li, J Tan… - Frontiers in …, 2022 - frontiersin.org
V-type immunoglobulin domain-containing suppressor of T cell activation (VISTA) is
considered as an immunosuppressive factor and potential therapeutic target for anticancer …

VISTA in hematological malignancies: a review of the literature

Y Duan, X Ren, X Guo, J **e, Z Liu, L Li - Frontiers in Immunology, 2024 - frontiersin.org
In recent years, tumor immunotherapy has become an active research area, with the
emergence of immune checkpoint inhibitors (ICIs) revolutionizing immunotherapy. Clinical …

Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy

AD Behsen, T Holien, F Micci, M Rye… - Scientific Reports, 2024 - nature.com
Multiple myeloma (MM) is a hematological malignancy originating from plasma cells.
Genetically, MM is categorized into two subtypes: hyperdiploid and non-hyperdiploid tumors …

Immune checkpoint expression patterns on T cell subsets in light-chain amyloidosis: VISTA, PD-1, and TIGIT as potential therapeutic targets

J Wang, Y Zhao, P Liao, S Huang, Y Huang, S Chen… - Blood Science, 2024 - mednexus.org
Amyloid light chain (AL) amyloidosis is a rare plasma cell dyscrasia with dismal prognosis.
This study aims to investigate the T-cell immune checkpoint expression patterns in systemic …

PD-1H expression associated with CD68 macrophage marker confers an immune-activated microenvironment and favorable overall survival in human esophageal …

Y Chen, R Feng, B He, J Wang, N **an… - Frontiers in Molecular …, 2021 - frontiersin.org
Esophageal squamous cell carcinoma (ESCC) is the most common type of esophageal
carcinoma (EC) in China. Although the PD-1 inhibitor pembrolizumab has been approved to …

Multiple myeloma and the potential of new checkpoint inhibitors for immunotherapy

AN Kamali, H Hamedifar, M Eisenhut… - … in Vaccines and …, 2024 - journals.sagepub.com
Multiple myeloma (MM), a cancer of the bone marrow, is categorized as the second most
common hematological malignancy of adults in the Western world. Despite dramatic …

Emerging therapies in Multiple Myeloma: Leveraging immune checkpoint inhibitors for improved outcomes

AA Mandavkar, SSN Padakanti, S Gupta… - Human …, 2025 - journals.sagepub.com
Background: Multiple Myeloma is a hematological malignancy characterized by the
proliferation of clonal plasma cells and associated with severe clinical manifestations …

Computational recognition of LncRNA signatures in tumor-associated neutrophils could have implications for immunotherapy and prognostic outcome of non-small …

Z Tang, Q Wang, P Chen, H Guo, J Shi, Y Pan… - Frontiers in …, 2022 - frontiersin.org
Cancer immune function and tumor microenvironment are governed by long noncoding
RNAs (lncRNAs). Nevertheless, it has yet to be established whether lncRNAs play a role in …