Respiratory syncytial virus: infection, detection, and new options for prevention and treatment

C Griffiths, SJ Drews, DJ Marchant - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

Respiratory syncytial virus infection in adults

HH Nam, MG Ison - bmj, 2019 - bmj.com
Human respiratory syncytial virus (RSV) belongs to the recently defined Pneumoviridae
family, Orthopneumovirus genus. It is a negative sense, single stranded RNA virus that …

Activity of oral ALS-008176 in a respiratory syncytial virus challenge study

JP DeVincenzo, MW McClure, JA Symons… - … England Journal of …, 2015 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) infection is a cause of substantial morbidity
and mortality. There is no known effective therapy. Methods We conducted a randomized …

The potential role of clinical metagenomics in infectious diseases: therapeutic perspectives

C d'Humières, M Salmona, S Dellière, S Leo… - Drugs, 2021 - Springer
Clinical metagenomics (CMg) is the process of sequencing nucleic acid of clinical samples
to obtain clinically relevant information such as the identification of microorganisms and their …

Deep sequencing of influenza A virus from a human challenge study reveals a selective bottleneck and only limited intrahost genetic diversification

A Sobel Leonard, MT McClain, GJD Smith… - Journal of …, 2016 - Am Soc Microbiol
Knowledge of influenza virus evolution at the point of transmission and at the intrahost level
remains limited, particularly for human hosts. Here, we analyze a unique viral data set of …

Molecular epidemiology of respiratory syncytial virus

KNA Pangesti, M Abd El Ghany… - Reviews in medical …, 2018 - Wiley Online Library
Respiratory syncytial virus (RSV) is a major cause of viral acute respiratory tract infections in
young children. The virus is characterised by distinct seasonality that is dependent upon the …

Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

GL Lin, SB Drysdale, MD Snape, D O'Connor… - Nature …, 2021 - nature.com
Human respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection
in young children globally, but little is known about within-host RSV diversity. Here, we …

Functional features of the respiratory syncytial virus G protein

LJ Anderson, SJ Jadhao, CR Paden, S Tong - Viruses, 2021 - mdpi.com
Respiratory syncytial virus (RSV) is a major cause of serious lower respiratory tract
infections in children< 5 years of age worldwide and repeated infections throughout life …

Respiratory syncytial virus: targeting the G protein provides a new approach for an old problem

RA Tripp, UF Power, PJM Openshaw… - Journal of virology, 2018 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection (LRTI)
annually affecting> 2 million children in the United States< 5 years old. In the elderly (> 65 …

Prolonged shedding of human coronavirus in hematopoietic cell transplant recipients: risk factors and viral genome evolution

C Ogimi, AL Greninger, AA Waghmare… - The Journal of …, 2017 - academic.oup.com
Background Recent data suggest that human coronavirus (HCoV) pneumonia is associated
with significant mortality in hematopoietic cell transplant (HCT) recipients. Investigation of …