Cancer therapy with antibodies

S Paul, MF Konig, DM Pardoll, C Bettegowda… - Nature Reviews …, 2024 - nature.com
The greatest challenge in cancer therapy is to eradicate cancer cells with minimal damage
to normal cells. Targeted therapy has been developed to meet that challenge, showing a …

Radiotheranostics global market and future developments

A Al-Ibraheem, R Zimmermann, AS Abdlkadir… - Seminars in Nuclear …, 2024 - Elsevier
Radiotheranostics, a combination of diagnostic and therapeutic approaches, was first
utilized in cancer management using radiopharmaceuticals to both image and selectively …

Actinium-225 targeted alpha particle therapy for prostate cancer

AP Bidkar, L Zerefa, S Yadav, HF VanBrocklin… - …, 2024 - pmc.ncbi.nlm.nih.gov
Targeted alpha particle therapy (TAT) has emerged as a promising strategy for the treatment
of prostate cancer (PCa). Actinium-225 (225Ac), a potent alpha-emitting radionuclide, may …

Radiotherapy and theranostics: A lancet oncology commission

M Abdel-Wahab, F Giammarile, M Carrara… - The lancet …, 2024 - thelancet.com
Following on from the 2015 Lancet Oncology Commission on expanding global access to
radiotherapy, Radiotherapy and theranostics: a Lancet Oncology Commission was created …

Recent advances and impending challenges for the radiopharmaceutical sciences in oncology

SE Lapi, PJH Scott, AM Scott, AD Windhorst… - The Lancet …, 2024 - thelancet.com
This paper is the first of a Series on theranostics that summarises the current landscape of
the radiopharmaceutical sciences as they pertain to oncology. In this Series paper, we …

Translating the theranostic concept to neuro-oncology: Disrupting barriers

NL Albert, E Le Rhun, G Minniti, MJ Mair… - The Lancet …, 2024 - thelancet.com
Theranostics integrate molecular imaging and targeted radionuclide therapy for
personalised cancer therapy. Theranostic treatments have shown meaningful efficacy in …

Salivary toxicity from PSMA-targeted radiopharmaceuticals: what we have learned and where we are going

M Muniz, CL Loprinzi, JJ Orme, RM Koch… - Cancer Treatment …, 2024 - Elsevier
Clinical trials of prostate-specific membrane antigen (PSMA) targeted radiopharmaceuticals
have shown encouraging results. Some agents, like lutetium-177 [177Lu] Lu-PSMA-617 …

[HTML][HTML] Advances in PSMA alpha theragnostics

M Vorster, M Sathekge - Seminars in Nuclear Medicine, 2024 - Elsevier
Alpha theranostics offer an attractive alternative form of therapy, which has best been
investigated and documented with 225 Ac-PSMA in patients with prostate cancer …

[HTML][HTML] Advancements in PSMA ligand radiolabeling for diagnosis and treatment of prostate cancer: a systematic review

Y Yan, H Zhuo, T Li, J Zhang, M Tan, Y Chen - Frontiers in Oncology, 2024 - frontiersin.org
Prostate cancer (PCa), a leading global health concern, profoundly impacts millions of men
worldwide. Progressing through two stages, it initially develops within the prostate and …

[HTML][HTML] Trends in cancer imaging

X Zhou, B Shi, G Huang, J Liu, W Wei - Trends in Cancer, 2024 - cell.com
Molecular imaging of cancer is a collaborative endeavor, uniting scientists and physicians
from diverse fields. Such collaboration is actively develo** and translating cutting-edge …