ATG9 vesicles comprise the seed membrane of mammalian autophagosomes
As the autophagosome forms, its membrane surface area expands rapidly, while its volume
is kept low. Protein-mediated transfer of lipids from another organelle to the autophagosome …
is kept low. Protein-mediated transfer of lipids from another organelle to the autophagosome …
Advancing membrane-associated protein docking with improved sampling and scoring in Rosetta
The oligomerization of protein macromolecules on cell membranes plays a fundamental role
in regulating cellular function. From modulating signal transduction to directing immune …
in regulating cellular function. From modulating signal transduction to directing immune …
Membrane extraction in native lipid nanodiscs reveals dynamic regulation of Cdc42 complexes during cell polarization
Embryonic development requires the establishment of cell polarity to enable cell fate
segregation and tissue morphogenesis. This process is regulated by Par complex proteins …
segregation and tissue morphogenesis. This process is regulated by Par complex proteins …
Cholesterol inhibits assembly and activation of the EphA2 receptor
RJ Schuck, AE Ward, AR Sahoo, JA Rybak… - …, 2024 - pmc.ncbi.nlm.nih.gov
The receptor tyrosine kinase EphA2 drives cancer malignancy by facilitating metastasis.
EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer …
EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer …
Cholesterol inhibits assembly and activation of the EphA2 receptor
RJ Schuck, AE Ward, AR Sahoo, JA Rybak, RJ Pyron… - bioRxiv, 2024 - biorxiv.org
The receptor tyrosine kinase EphA2 drives cancer malignancy by facilitating metastasis.
EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer …
EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer …
Early and Late Stage Mechanisms of Autophagosome Formation
TJ Olivas - 2023 - search.proquest.com
During autophagosome biogenesis, the incorporation of transmembrane proteins into the
expanding phagophore is not readily observed. In addition, the membrane surface area of …
expanding phagophore is not readily observed. In addition, the membrane surface area of …