Hypertension management in older and frail older patients

A Benetos, M Petrovic, T Strandberg - Circulation research, 2019 - ahajournals.org
The prevalence of arterial hypertension, particularly systolic hypertension, is constantly
rising worldwide. This is mainly the clinical expression of arterial stiffening as a result of the …

2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of …

B Williams, G Mancia, W Spiering… - European heart …, 2018 - academic.oup.com
Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

Neurovascular and cognitive dysfunction in hypertension: epidemiology, pathobiology, and treatment

C Iadecola, RF Gottesman - Circulation research, 2019 - ahajournals.org
Hypertension has emerged as a leading cause of age-related cognitive impairment. Long
known to be associated with dementia caused by vascular factors, hypertension has more …

Inflammation and cerebral small vessel disease: a systematic review

A Low, E Mak, JB Rowe, HS Markus, JT O'Brien - Ageing research reviews, 2019 - Elsevier
Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …

[PDF][PDF] Guía ESC/ESH 2018 sobre el diagnóstico y tratamiento de la hipertensión arterial

B Williams, G Mancia, W Spiering, E Agabiti Rosei… - Rev Esp …, 2019 - peroxfarma.com
La tarea de elaboración de GPC incluye la creación de herramientas educativas y
programas de implementación de las recomendaciones. Para su implementación, se …

Recommendations for improving and standardizing vascular research on arterial stiffness: a scientific statement from the American Heart Association

RR Townsend, IB Wilkinson, EL Schiffrin, AP Avolio… - …, 2015 - ahajournals.org
Townsend et al Vascular Research on Arterial Stiffness 699 pressure, blood flow, and
arterial diameter change with each heartbeat. In addition to the passive mechanical …

[PDF][PDF] 2013 ESH/ESC Guidelines for the management of arterial hypertension

G Mancia, R Fagard, K Narkiewicz… - Arterial …, 2013 - journals.viamedica.pl
Wytyczne dotyczące nadciśnienia tętniczego opublikowane w 2013 r. przez Europejskie
Towarzystwo Nadciśnienia Tętniczego (ESH) i Europejskie Towarzystwo Kardiologiczne …

The pathobiology of vascular dementia

C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …

PB Gorelick, A Scuteri, SE Black, C DeCarli… - stroke, 2011 - ahajournals.org
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility–Reykjavik study

GF Mitchell, MA Van Buchem, S Sigurdsson, JD Gotal… - Brain, 2011 - academic.oup.com
Aortic stiffness increases with age and vascular risk factor exposure and is associated with
increased risk for structural and functional abnormalities in the brain. High ambient flow and …