Chloroquine and Chemotherapeutic Compounds in Experimental Cancer Treatment
NI Agalakova - International Journal of Molecular Sciences, 2024 - mdpi.com
Chloroquine (CQ) and its derivate hydroxychloroquine (HCQ), the compounds with
recognized ability to suppress autophagy, have been tested in experimental works and in …
recognized ability to suppress autophagy, have been tested in experimental works and in …
The African Kelleni's roadmap using nitazoxanide and broad-spectrum antimicrobials to abort returning to COVID-19 square one
MT Kelleni - Inflammopharmacology, 2023 - Springer
Abstract For over 3.5 years, SARS CoV-2 is continuing to evolve threatening to return all and
any improvement the world has made into square one. In this clinically oriented systematic …
any improvement the world has made into square one. In this clinically oriented systematic …
Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
P Glajzner, A Bernat… - Frontiers in …, 2024 - frontiersin.org
Drug repurposing (repositioning) is a dynamically-develo** area in the search for effective
therapy of infectious diseases. Repositioning existing drugs with a well-known …
therapy of infectious diseases. Repositioning existing drugs with a well-known …
Network analysis-guided drug repurposing strategies targeting LPAR receptor in the interplay of COVID, Alzheimer's, and diabetes
The COVID-19 pandemic caused by the SARS-CoV-2 virus has greatly affected global
health. Emerging evidence suggests a complex interplay between Alzheimer's disease (AD) …
health. Emerging evidence suggests a complex interplay between Alzheimer's disease (AD) …
A weighted integration method based on graph representation learning for drug repositioning
H Lian, P Ding, C Yu, X Zhang, G Liu, B Yu - Applied Soft Computing, 2024 - Elsevier
The time-consuming and expensive nature of traditional drug discovery necessitates a cost-
effective approach to facilitate disease treatment. Drug repositioning, discovering innovative …
effective approach to facilitate disease treatment. Drug repositioning, discovering innovative …
Multidimensional role of adapalene in regulating cell death in multiple myeloma
X Cao, J **ang, Q Zhang, J Liu, D Zhou, Y Xu… - Frontiers in …, 2024 - frontiersin.org
Aims Multiple myeloma (MM) remains a challenging condition to cure, with persistent drug
resistance negating the benefits of treatment advancements. The unraveling complexities in …
resistance negating the benefits of treatment advancements. The unraveling complexities in …
Drug Repurposing and Lysosomal Storage Disorders: A Trick to Treat
Rare diseases, or orphan diseases, are defined as diseases affecting a small number of
people compared to the general population. Among these, we find lysosomal storage …
people compared to the general population. Among these, we find lysosomal storage …
Physicochemical modeling and characterization of the adsorption mechanism of seven pharmaceutical molecules onto SARS-CoV-2 virus
O Kouira, S Bayoudh, H Smati, M Bouzid… - Materials Chemistry and …, 2023 - Elsevier
The aim of this work is to facilitate the fight against COVID-19 pandemic using a comparative
study of seven drug molecules, in order to select the most efficient drug molecules. This …
study of seven drug molecules, in order to select the most efficient drug molecules. This …
Unraveling the Role of PCDH9 in Breast Cancer and Identifying Therapeutic Strategies for PCDH9-Deficient Tumors
R Li, L Liu, Y Liu, J Tang, J Li - Breast Cancer: Targets and …, 2024 - Taylor & Francis
Introduction Protocadherin 9 (PCDH9), a member of the cadherin superfamily of
transmembrane proteins, plays a role in cell adhesion and neural development. Recent …
transmembrane proteins, plays a role in cell adhesion and neural development. Recent …
Antibiotic consumption in French nursing homes between 2018 and 2022: A multicenter survey
S Bouges, A Jouzeau, F Lieutier-Colas… - Infection Control & …, 2024 - cambridge.org
Objectives: Monitoring antibiotic consumption is a key component to steer antimicrobial
stewardship programs, including in nursing homes. We analyzed changes in antibiotic …
stewardship programs, including in nursing homes. We analyzed changes in antibiotic …