Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

The acute respiratory distress syndrome

LB Ware, MA Matthay - New England Journal of Medicine, 2000 - Mass Medical Soc
The acute respiratory distress syndrome is a common, devastating clinical syndrome of
acute lung injury that affects both medical and surgical patients. Since the last review of this …

The American–European Consensus Conference on ARDS, part 2: ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to …

A Artigas, GR Bernard, J Carlet, D Dreyfuss… - American journal of …, 1998 - atsjournals.org
The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity
and mortality of patients in intensive care units throughout the world, imparting tremendous …

Pathophysiology of acute lung injury and the acute respiratory distress syndrome

LB Ware - Seminars in respiratory and critical care medicine, 2006 - thieme-connect.com
Since the adult respiratory distress syndrome was first described substantial progress has
been made in understanding the pathogenesis of this complex syndrome. This review …

Pulmonary pathology of acute respiratory distress syndrome

JF Tomashefski Jr - Clinics in chest medicine, 2000 - Elsevier
Acute respiratory distress syndrome (ARDS) encompasses a relatively uniform constellation
of clinical, radiographic, and physiologic features in patients with rapidly evolving respiratory …

The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis.

C Kuhn, JA McDonald - The American journal of pathology, 1991 - ncbi.nlm.nih.gov
The synthesis of collagen and EIIIA-containing cellular fibronectin in certain forms of
pulmonary fibrosis occurs in discrete locations: in the Masson bodies in bronchiolitis …

TGF-β1-mediated fibroblast–myofibroblast terminal differentiation—the role of smad proteins

RA Evans, YC Tian, R Steadman, AO Phillips - Experimental cell research, 2003 - Elsevier
It is now clear that resident myofibroblasts play a central role in the mediation of tissue
fibrosis. The aim of the work outlined in this study is to increase our understanding of the …

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.

DT Eitzman, RD McCoy, X Zheng… - The Journal of …, 1996 - Am Soc Clin Investig
Impaired fibrinolytic activity within the lung is a common manifestation of acute and chronic
inflammatory lung diseases. Because the fibrinolytic system is active during repair …

Organising pneumonia

JF Cordier - Thorax, 2000 - thorax.bmj.com
Organising pneumonia is defined pathologically by the presence in the distal air spaces of
buds of granulation tissue progressing from fibrin exudates to loose collagen containing …

From the radiologic pathology archives: organization and fibrosis as a response to lung injury in diffuse alveolar damage, organizing pneumonia, and acute fibrinous …

SJ Kligerman, TJ Franks, JR Galvin - Radiographics, 2013 - pubs.rsna.org
Organization, characterized by fibroblast proliferation, is a common and nearly universal
response to lung injury whether it is focal or diffuse. Despite the vast range of injurious …