Endothelial dysfunction is involved in the development of atherosclerosis, which precedes
asymptomatic structural vascular alterations as well as clinical manifestations of …

The vascular endothelium is a multifunctional cellular system which directly influences blood
components and cells within the vessel wall in a given tissue. Importantly, this cellular …

In Japan, a super-aged society, deaths from atherosclerotic cardiovascular disease
(ASCVD), especially cardiac diseases including coronary artery disease (CAD) such as …

Every 5 years, the JAS publishes guidelines for the treatment of dyslipidemia and
atherosclerosis. To date, this society has released four such guidelines. Since 2007, the JAS …

Background: Although lifestyle modifications generally are effective in lowering blood
pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or …

Briefly, measurement of flow-mediated vasodilation (FMD) of the brachial artery has been
used for the assessment of endothelial function in humans. 14, 15 This technique measures …

Endothelial dysfunction is now considered an important early event in the development of
atherosclerosis, which precedes gross morphological signs and clinical symptoms. The …

Note: Authors from the National Institutes of Health/National Heart, Lung, and Blood Institute
represent themselves and not the opinions of the National Institutes of Health/National …

Endothelial function is thought to be an important factor in the pathogenesis of
atherosclerosis, hypertension and heart failure. In the 1990s, high-frequency …

As the major regulator of vascular homeostasis, the endothelium exerts a number of
vasoprotective effects, such as vasodilation, suppression of smooth muscle cell growth, and …