Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its
derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this …

Metallodrugs offer potential for unique mechanisms of drug action based on the choice of
the metal, its oxidation state, the types and number of coordinated ligands and the …

Organometallic complexes containing ligands such as CO, carbenes, alkyls, phenyls, π-
bound alkynes, alkenes, cyclopentadienyls and arenes possess properties which have often …

Conspectus Iridium is a relatively rare precious heavy metal, only slightly less dense than
osmium. Researchers have long recognized the catalytic properties of square-planar IrI …

Octahedral Ir (III) complexes bearing cyclometalated ligands exhibit a great stability in
biological media and are excellent therapeutical and phototherapeutical candidates for …

The clinical success of the platinum-based chemotherapeutic agents has prompted the
investigation of coordination and organometallic complexes of alternative metal centers for …

Platinum complexes are widely used anticancer drugs. New generations of metal
chemotherapeutics offer the prospect of combating platinum resistance and expanding the …

Organelle specificity is an important facet of more efficient and highly selective drugs with
reduced side effects which have now been the great challenge to the scientists. In …

Boron dipyrromethene, commonly known as BODIPY, based metal–organic macrocycles
(MOCs) and metal–organic frameworks (MOFs) represent an interesting part of materials …