2023 ESC Guidelines for the management of cardiomyopathies: Developed by the task force on the management of cardiomyopathies of the European Society of …

E Arbelo, A Protonotarios, JR Gimeno… - European heart …, 2023‏ - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

2024 AHA/ACC/AMSSM/HRS/PACES/SCMR guideline for the management of hypertrophic cardiomyopathy: a report of the American Heart Association/American …

Writing Committee Members, SR Ommen… - Journal of the American …, 2024‏ - jacc.org
Abstract Aim The “2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the
Management of Hypertrophic Cardiomyopathy” provides recommendations to guide …

Diagnosis and Evaluation of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review

BJ Maron, MY Desai, RA Nishimura, P Spirito… - Journal of the American …, 2022‏ - jacc.org
Hypertrophic cardiomyopathy (HCM) is a relatively common often inherited global heart
disease, with complex phenotypic and genetic expression and natural history, affecting both …

Phase 2 study of aficamten in patients with obstructive hypertrophic cardiomyopathy

MS Maron, A Masri, L Choudhury, I Olivotto… - Journal of the American …, 2023‏ - jacc.org
Background Left ventricular outflow tract (LVOT) obstruction is a major determinant of heart
failure symptoms in obstructive hypertrophic cardiomyopathy (oHCM). Aficamten, a next-in …

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: a report of the American College of Cardiology/American …

SR Ommen, S Mital, MA Burke, SM Day… - Journal of the American …, 2020‏ - jacc.org
The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: executive summary: a report of the American College of …

SR Ommen, S Mital, MA Burke, SM Day… - Journal of the American …, 2020‏ - jacc.org
Aim This executive summary of the hypertrophic cardiomyopathy clinical practice guideline
provides recommendations and algorithms for clinicians to diagnose and manage …

Mavacamten: a first-in-class myosin inhibitor for obstructive hypertrophic cardiomyopathy

E Braunwald, S Saberi, TP Abraham… - European Heart …, 2023‏ - academic.oup.com
Mavacamten is a first-in-class, targeted, cardiac-specific myosin inhibitor approved by the
US Food and Drug Administration for the treatment of adults with symptomatic New York …

Clinical course and management of hypertrophic cardiomyopathy

BJ Maron - New England Journal of Medicine, 2018‏ - Mass Medical Soc
Hypertrophic Cardiomyopathy HCM is the most common genetic disorder of the heart, with 1
case per 200 to 500 persons, and often remains clinically silent. HCM is the most common …

Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy

AJ Marian, E Braunwald - Circulation research, 2017‏ - ahajournals.org
Hypertrophic cardiomyopathy (HCM) is a genetic disorder that is characterized by left
ventricular hypertrophy unexplained by secondary causes and a nondilated left ventricle …

Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology

PM Seferović, M Polovina, J Bauersachs… - European journal of …, 2019‏ - Wiley Online Library
Cardiomyopathies are a heterogeneous group of heart muscle diseases and an important
cause of heart failure (HF). Current knowledge on incidence, pathophysiology and natural …