Role of mitochondria in radiation responses: epigenetic, metabolic, and signaling impacts

D Averbeck, C Rodriguez-Lafrasse - International journal of molecular …, 2021 - mdpi.com
Until recently, radiation effects have been considered to be mainly due to nuclear DNA
damage and their management by repair mechanisms. However, molecular biology studies …

Nanotechnology applications in breast cancer immunotherapy

R Wang, P Kumar, M Reda, AG Wallstrum… - Small, 2024 - Wiley Online Library
Next‐generation cancer treatments are expected not only to target cancer cells but also to
simultaneously train immune cells to combat cancer while modulating the immune …

Ferroptosis, necroptosis, and pyroptosis in cancer: Crucial cell death types in radiotherapy and post-radiotherapy immune activation

Y Wang, Y Wang, J Pan, L Gan, J Xue - Radiotherapy and Oncology, 2023 - Elsevier
Tumor cell death and antitumor immune activation induced by radiotherapy are extensively
well-studied. While radiotherapy is believed to mainly induce tumor cell necrosis and …

Cytotoxicity of PEG-Coated Gold and Gold–Iron Alloy Nanoparticles: ROS or Ferroptosis?

CMG de Faria, M Bissoli, R Vago, AE Spinelli… - Nanomaterials, 2023 - mdpi.com
Nanomedicine relies on the exploitation of nanoscale constructs for therapeutic and
diagnostic functions. Gold and gold–iron alloy nanoparticles (NPs) are two examples of …

The advances in epigenetics for cancer radiotherapy

Y Wang, Y Han, Y **, Q He, Z Wang - International Journal of Molecular …, 2022 - mdpi.com
Cancer is an important factor threatening human life and health; in recent years, its morbidity
and mortality remain high and demosntrate an upward trend. It is of great significance to …

[HTML][HTML] Future of Team-based Basic and Translational Science in Radiation Oncology

RP Coppes, LV van Dijk - Seminars in radiation oncology, 2024 - Elsevier
To further optimize radiotherapy, a more personalized treatment towards individual patient's
risk profiles, dissecting both patient-specific tumor and normal tissue response to …

[HTML][HTML] The oxygen puzzle in FLASH radiotherapy: A comprehensive review and experimental outlook

A Scarmelotto, V Delprat, C Michiels, S Lucas… - Clinical and translational …, 2024 - Elsevier
FLASH radiotherapy is attracting increasing interest because it maintains tumor control while
inflicting less damage to normal tissues compared to conventional radiotherapy. This …

Effective combination of isoniazid and core-shell magnetic nanoradiotherapy against gastrointestinal tumor cell types

H Chen, D Zhu, L Guo, G Li - International Journal of …, 2022 - Taylor & Francis
Introduction Radiotherapy is a conventional treatment for gastrointestinal tumors. However,
its therapeutic effect might not be satisfactory because of factors such as radio-resistance of …

Nanomaterials-based advanced systems for photothermal/photodynamic therapy of oral cancer

Y Wang, L Chang, H Gao, C Yu, Y Gao… - European Journal of …, 2024 - Elsevier
The traditional clinical approaches for oral cancer consist of surgery, chemotherapy,
radiotherapy, immunotherapy, and so on. However, these treatments often induce side …

Rapid synthesis of 'yolk-shell'-like nanosystem for MR molecular and chemo-radio sensitization

M Hou, K Zhu, H Hu, S Zheng, Z Wu, Y Ren… - Journal of Controlled …, 2022 - Elsevier
Though amounts of attempts about nanomedicine for chemo-radiotherapy have been made,
more efficient strategies for chemo-radio therapy enhancement still need to be studied and …