The management of retinoblastoma

ID Fabian, Z Onadim, E Karaa, C Duncan… - Oncogene, 2018 - nature.com
Retinoblastoma (Rb) is the most common primary intraocular malignancy of childhood, but
an uncommon paediatric cancer, with a constant incidence worldwide of 1: 15,000–1 …

Conservative management of retinoblastoma: Challenging orthodoxy without compromising the state of metastatic grace.“Alive, with good vision and no comorbidity”

FL Munier, M Beck-Popovic, GL Chantada… - Progress in retinal and …, 2019 - Elsevier
Retinoblastoma is lethal by metastasis if left untreated, so the primary goal of therapy is to
preserve life, with ocular survival, visual preservation and quality of life as secondary aims …

The International Classification of Retinoblastoma predicts chemoreduction success

CL Shields, A Mashayekhi, AK Au, C Czyz, A Leahey… - Ophthalmology, 2006 - Elsevier
PURPOSE: To evaluate the reliability of the International Classification of Retinoblastoma
(ICRB) for predicting treatment success with chemoreduction (CRD). DESIGN …

Retinoblastoma management: advances in enucleation, intravenous chemoreduction, and intra-arterial chemotherapy

CL Shields, JA Shields - Current opinion in ophthalmology, 2010 - journals.lww.com
Progress has been made in the past few years in the management of retinoblastoma with
better enucleation implants, chemoreduction-prevention of pinealoblastoma and excellent …

Retinoblastoma frontiers with intravenous, intra-arterial, periocular, and intravitreal chemotherapy

CL Shields, EM Fulco, JD Arias, C Alarcon, M Pellegrini… - Eye, 2013 - nature.com
In this report, we explore retinoblastoma diagnostic accuracy and review chemotherapy
alternatives for retinoblastoma using intravenous, intra-arterial, periocular, and intravitreal …

Intra-arterial chemotherapy in retinoblastoma–A paradigm change

FP Manjandavida, C Stathopoulos… - Indian journal of …, 2019 - journals.lww.com
Abstract Intra-arterial chemotherapy (IAC), also known as superselective ophthalmic artery
chemotherapy or chemosurgery, is currently widely accepted as one of the primary treatment …

Targeted retinoblastoma management: when to use intravenous, intra-arterial, periocular, and intravitreal chemotherapy

CL Shields, SE Lally, AM Leahey… - Current opinion in …, 2014 - journals.lww.com
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Selective ophthalmic arterial injection therapy for intraocular retinoblastoma: the long-term prognosis

S Suzuki, T Yamane, M Mohri, A Kaneko - Ophthalmology, 2011 - Elsevier
PURPOSE: To report the success rate, adverse events, and long-term prognosis of selective
ophthalmic arterial injection (SOAI) therapy for intraocular retinoblastoma. DESIGN …

Update on retinoblastoma

DH Abramson, AC Schefler - Retina, 2004 - journals.lww.com
After completion of this article, the reader will be able to 1) state the therapeutic interventions
that are currently used to treat intraocular retinoblastoma, and to outline the mechanism of …

Incidence of second cancers after radiotherapy and systemic chemotherapy in heritable retinoblastoma survivors: a report from the German reference center

P Temming, M Arendt, A Viehmann… - Pediatric blood & …, 2017 - Wiley Online Library
Background Survivors of heritable retinoblastoma carry a high risk to develop second
cancers. Eye‐preserving radiotherapy raises this risk, while the impact of chemotherapy …