[HTML][HTML] Co-ordinated assembly of the multilayered cell envelope of Gram-negative bacteria

EM Fivenson, L Dubois, TG Bernhardt - Current Opinion in Microbiology, 2024 - Elsevier
Bacteria surround themselves with complex cell envelopes to maintain their integrity and
protect against external insults. The envelope of Gram-negative organisms is multilayered …

The divergent early divisome: is there a functional core?

G Santiago-Collazo, PJB Brown, AM Randich - Trends in Microbiology, 2024 - cell.com
The bacterial divisome is a complex nanomachine that drives cell division and separation.
The essentiality of these processes leads to the assumption that proteins with core roles will …

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

ECA Goodall, GL Isom, JL Rooke, K Pullela… - PLoS …, 2021 - journals.plos.org
The cell envelope is essential for viability in all domains of life. It retains enzymes and
substrates within a confined space while providing a protective barrier to the external …

Early midcell localization of Escherichia coli PBP4 supports the function of peptidoglycan amidases

J Verheul, A Lodge, HCL Yau, X Liu, G Boelter… - PLoS …, 2022 - journals.plos.org
Insertion of new material into the Escherichia coli peptidoglycan (PG) sacculus between the
cytoplasmic membrane and the outer membrane requires a well-organized balance …

CRISPR–dCas13a system for programmable small RNAs and polycistronic mRNA repression in bacteria

SC Ko, HM Woo - Nucleic Acids Research, 2024 - academic.oup.com
Bacterial small RNAs (sRNAs) function in post-transcriptional regulatory responses to
environmental changes. However, the lack of eukaryotic RNA interference-like machinery in …

Roles of RodZ and class A PBP1b in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid‐shaped cells of Streptococcus pneumoniae …

MM Lamanna, I Manzoor, M Joseph, ZA Ye… - Molecular …, 2022 - Wiley Online Library
RodZ of rod‐shaped bacteria functions to link MreB filaments to the Rod peptidoglycan (PG)
synthase complex that moves circumferentially perpendicular to the long cell axis, creating …

Loss of YhcB results in overactive fatty acid biosynthesis

HM Stanley, MS Trent - Mbio, 2024 - journals.asm.org
Loss of the Escherichia coli inner membrane protein YhcB results in pleomorphic cell
morphology and clear growth defects. Prior work suggested that YhcB was directly involved …

[HTML][HTML] A new factor LapD is required for the regulation of LpxC amounts and lipopolysaccharide trafficking

A Wieczorek, A Sendobra, A Maniyeri… - International Journal of …, 2022 - mdpi.com
Lipopolysaccharide (LPS) constitutes the major component of the outer membrane and is
essential for bacteria, such as Escherichia coli. Recent work has revealed the essential roles …

[HTML][HTML] Suppressors of lapC Mutation Identify New Regulators of LpxC, Which Mediates the First Committed Step in Lipopolysaccharide Biosynthesis

A Maniyeri, A Wieczorek, A Ayyolath… - International Journal of …, 2023 - mdpi.com
Gram-negative bacteria, such as Escherichia coli, are characterized by an asymmetric outer
membrane (OM) with lipopolysaccharide (LPS) located in the outer leaflet and …

Midcell localization of PBP4 of Escherichia coli is essential for the timing of divisome assembly

J Verheul, A Lodge, HCL Yau, X Liu, AS Solovyova… - bioRxiv, 2020 - biorxiv.org
Insertion of new material into the Escherichia coli peptidoglycan (PG) sacculus between the
cytoplasmic membrane and the outer membrane requires a well-organized balance …