Criteria for pediatric sepsis—a systematic review and meta-analysis by the pediatric sepsis definition taskforce

K Menon, LJ Schlapbach, S Akech, A Argent… - Critical care …, 2022 - journals.lww.com
Objective: To determine the associations of demographic, clinical, laboratory, organ
dysfunction, and illness severity variable values with: 1) sepsis, severe sepsis, or septic …

International consensus criteria for pediatric sepsis and septic shock

LJ Schlapbach, RS Watson, LR Sorce, AC Argent… - JAMA, 2024 - jamanetwork.com
Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-
specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the …

Pediatric sepsis: a summary of current definitions and management recommendations

M Miranda, S Nadel - Current Pediatrics Reports, 2023 - Springer
Abstract Purpose of Review Pediatric sepsis remains an important cause of morbidity and
mortality in children. This review will summarize the main aspects of the definition, the …

The current and future state of pediatric sepsis definitions: an international survey

L Morin, M Hall, D de Souza, L Guo**… - …, 2022 - publications.aap.org
METHODS This is an international electronic survey of clinicians distributed across
international and national societies representing pediatric intensive care, emergency …

Latin American consensus on the management of sepsis in children: sociedad latinoamericana de cuidados intensivos pediátricos [Latin American Pediatric Intensive …

J Fernández-Sarmiento, DC De Souza… - Journal of intensive …, 2022 - journals.sagepub.com
Objective: The aim of this study was to develop evidence-based recommendations for the
diagnosis and treatment of sepsis in children in low-and middle-income countries (LMICs) …

Validation of the pediatric sequential organ failure assessment score and evaluation of third international consensus definitions for sepsis and septic shock definitions …

F Balamuth, HF Scott, SL Weiss, M Webb… - JAMA …, 2022 - jamanetwork.com
Importance Pediatric sepsis definitions have evolved, and some have proposed using the
measure used in adults to quantify organ dysfunction, a Sequential Organ Failure …

Anti-inflammatory and anti-biotic drug metronidazole loaded ZIF-90 nanoparticles as a pH responsive drug delivery system for improved pediatric sepsis management

T Lin, T Qin, S Jiang, C Zhang, L Wang - Microbial Pathogenesis, 2023 - Elsevier
Sepsis is a life-threatening disease caused by the dis-functioning of the immune response to
pathogenic infections. Despite, the discovery of modern therapeutics and treatments of …

[HTML][HTML] The state-of-the-art therapeutic paradigms against sepsis

I Saha, N Bag, S Roy, Z Ullah, S Bardhan… - Smart Materials in …, 2024 - Elsevier
Sepsis frequently leads to life-threatening organ failure due to an in appropriate response by
the body to bacterial, viral, and fungal infections. In recent years, there has been an …

Reporting of social determinants of health in pediatric sepsis studies

K Menon, LR Sorce, A Argent, TD Bennett… - Pediatric Critical Care …, 2023 - journals.lww.com
OBJECTIVE: Standardized, consistent reporting of social determinants of health (SDOH) in
studies on children with sepsis would allow for: 1) understanding the association of SDOH …

Clinical decision support tools for paediatric sepsis in resource-poor settings: an international qualitative study

A Jimenez-Zambrano, C Ritger, M Rebull, MO Wiens… - BMJ open, 2023 - bmjopen.bmj.com
Objective New paediatric sepsis criteria are being developed by an international task force.
However, it remains unknown what type of clinical decision support (CDS) tools will be most …