Organotins: a review of their reproductive toxicity, biochemistry, and environmental fate

JB Graceli, GC Sena, PFI Lopes, GC Zamprogno… - Reproductive …, 2013 - Elsevier
The review purposes are to (1) evaluate the experimental evidence for adverse effects on
reproduction and metabolism and (2) identify the current knowledge of analytical …

[HTML][HTML] Adipocytes under assault: environmental disruption of adipose physiology

SM Regnier, RM Sargis - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
The burgeoning obesity epidemic has placed enormous strains on individual and societal
health mandating a careful search for pathogenic factors, including the contributions made …

Hemotin, a regulator of phagocytosis encoded by a small ORF and conserved across metazoans

JI Pueyo, EG Magny, CJ Sampson, U Amin… - PLoS …, 2016 - journals.plos.org
Translation of hundreds of small ORFs (smORFs) of less than 100 amino acids has recently
been revealed in vertebrates and Drosophila. Some of these peptides have essential and …

Subacute and low dose of tributyltin exposure leads to brown adipose abnormalities in male rats

E Merlo, J Zimerman, FCF Dos Santos, JF Zanol… - Toxicology letters, 2023 - Elsevier
Tributyltin (TBT) is an obesogenic endocrine disrupting chemical (EDC) linked with several
metabolic complications. Brown adipose tissue (BAT) is the principal site for thermogenesis …

Tributyltin impacts in metabolic syndrome development through disruption of angiotensin II receptor signaling pathways in white adipose tissue from adult female rats

LC Freitas-Lima, E Merlo, MC Zicker, JM Navia-Pelaez… - Toxicology Letters, 2018 - Elsevier
White adipose tissue (WAT) dysfunction and obesity are a consequence of a low-grade
inflammation state. These WAT irregularities could result from abnormal metabolic renin …

In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db …

J Sandström, DV Kratschmar, A Broyer, O Poirot… - Archives of …, 2019 - Springer
Brain susceptibility to a neurotoxic insult may be increased in a compromised health status,
such as metabolic syndrome. Both metabolic syndrome and exposure to trimethyltin (TMT) …

Effects of leptin, ghrelin and neuropeptide y on spike-wave discharge activity and certain biochemical parameters in WAG/Rij rats with genetic absence epilepsy

B Oztas, D Sahin, H Kir, S Kuskay, N Ates - Journal of Neuroimmunology, 2021 - Elsevier
This study aimed to evaluate the effects of leptin, ghrelin and neuropeptide-Y on the
development of nonconvulsive seizure activity and their role on combating oxidative stress …

Redox status on different regions of the central nervous system of obese and lean rats treated with green tea extract

RC Macedo, EF Bondan, R Otton - Nutritional Neuroscience, 2019 - Taylor & Francis
Objectives: The purpose of this study was to evaluate some indicators of redox status, and
inflammation on different regions of the central nervous system (CNS) of obese rats treated …

[PDF][PDF] AVALIAÇÃO DA EXPOSIÇÃO AO TRIBUTILESTANHO NOS PARÂMETROS MORFOLÓGICOS E METABÓLICOS EM RATOS EXPOSTOS AO FRIO

E Merlo - 2022 - sappg.ufes.br
1. RESUMO O cloreto de tributilestanho (TBT) é um obesogênico associado a várias
complicações metabólicas. O tecido adiposo marrom (TAM) é um alvo emergente que pode …

Propentofylline decreases hypothalamic astrogliosis induced by hypercaloric diet in the rat

EF Bondan, CC Vieira, MFM Martins… - Arquivos de neuro …, 2018 - SciELO Brasil
Obesity is associated with a chronic and low-grade inflammatory response in the
hypothalamus, where astrogliosis occurs with the upregulation of the astrocyte structural …