Biosynthesis, evolution and ecology of microbial terpenoids

M Avalos, P Garbeva, L Vader, GP van Wezel… - Natural Product …, 2022 - pubs.rsc.org
Covering: through June 2021 Terpenoids are the largest class of natural products
recognised to date. While mostly known to humans as bioactive plant metabolites and part of …

Macrofungi: A review of cultivation strategies, bioactivity, and application of mushrooms

H Lu, H Lou, J Hu, Z Liu, Q Chen - Comprehensive reviews in …, 2020 - Wiley Online Library
The production of macrofungi (mushrooms) as well as their economic value have been
steadily increasing globally. The use of functional foods, dietary supplements, and traditional …

Therapeutic potential of fungal terpenes and terpenoids: application in skin diseases

M Trepa, K Sułkowska-Ziaja, K Kała, B Muszyńska - Molecules, 2024 - mdpi.com
Terpenes and their derivatives comprise a diverse group of natural compounds with
versatile medicinal properties. This article elucidates the general characteristics of fungal …

Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota

M Gressler, NA Löhr, T Schäfer, S Lawrinowitz… - Natural product …, 2021 - pubs.rsc.org
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota
have traditionally been recognised as prolific producers of structurally diverse and often …

[PDF][PDF] Fungi-on-a-Chip: microfluidic platforms for single-cell studies on fungi

F Richter, S Bindschedler… - FEMS Microbiology …, 2022 - academic.oup.com
This review highlights new advances in the emerging field of 'Fungi-on-a-Chip'microfluidics
for single-cell studies on fungi and discusses several future frontiers, where we envisage …

Chromatin-dependent regulation of secondary metabolite biosynthesis in fungi: is the picture complete?

J Collemare, MF Seidl - FEMS microbiology reviews, 2019 - academic.oup.com
Fungal secondary metabolites are small molecules that exhibit diverse biological activities
exploited in medicine, industry and agriculture. Their biosynthesis is governed by co …

[HTML][HTML] Beyond Penicillin: the potential of filamentous fungi for drug discovery in the age of antibiotic resistance

J Correia, A Borges, M Simões, LC Simões - Antibiotics, 2023 - mdpi.com
Antibiotics are a staple in current medicine for the therapy of infectious diseases. However,
their extensive use and misuse, combined with the high adaptability of bacteria, has …

Coprinopsis cinerea uses laccase Lcc9 as a defense strategy to eliminate oxidative stress during fungal‐fungal interactions

J Liu, C Peng, Q Han, M Wang, G Zhou… - Applied and …, 2022 - journals.asm.org
Frequently, laccases are triggered during fungal cocultivation for overexpression. The
function of these activated laccases during coculture has not been clarified. Previously, we …

Predicting functions of putative fungal sesquiterpene synthase genes based on multiomics data analysis

T Nosenko, I Zimmer, A Ghirardo, TG Köllner… - Fungal genetics and …, 2023 - Elsevier
Sesquiterpenes (STs) are secondary metabolites, which mediate biotic interactions between
different organisms. Predicting the species-specific ST repertoires can contribute to …

Bifurcate evolution of quinone synthetases in basidiomycetes

PS Seibold, S Lawrinowitz, I Raztsou… - Fungal Biology and …, 2023 - Springer
Background The terphenylquinones represent an ecologically remarkable class of
basidiomycete natural products as they serve as central precursors of pigments and …