Intestinal barrier function in health and disease—any role of SARS-CoV-2?

L Sharma, A Riva - Microorganisms, 2020 - mdpi.com
Alterations in the structure and function of the intestinal barrier play a role in the
pathogenesis of a multitude of diseases. During the recent and ongoing coronavirus disease …

NSAID-associated small intestinal injury: an overview from animal model development to pathogenesis, treatment, and prevention

M Zhang, F **a, S **a, W Zhou, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
With the wide application of non-steroidal anti-inflammatory drugs (NSAIDs), their
gastrointestinal side effects are an urgent health burden. There are currently sound …

Widely available lysosome targeting agents should be considered as potential therapy for COVID-19

J Homolak, I Kodvanj - International journal of antimicrobial agents, 2020 - Elsevier
While the coronavirus disease 2019 (COVID-19) pandemic advances, the scientific
community continues to struggle in the search for treatments. Several improvements have …

Antioxidant and Anti-Inflammatory Activities of Cytocompatible Salvia officinalis Extracts: A Comparison between Traditional and Soxhlet Extraction

SF Vieira, H Ferreira, NM Neves - Antioxidants, 2020 - mdpi.com
Chronic inflammation is characterized by an overproduction of several inflammatory
mediators (eg, reactive species and interleukins-IL) that play a central role in numerous …

Echinacea purpurea Fractions Represent Promising Plant-Based Anti-Inflammatory Formulations

SF Vieira, SM Gonçalves, VMF Gonçalves, CP Llaguno… - Antioxidants, 2023 - mdpi.com
Echinacea purpurea is traditionally used in the treatment of inflammatory diseases.
Therefore, we investigated the anti-inflammatory capacity of E. purpurea dichloromethanolic …

Platinum (IV)-estramustine multiaction prodrugs are effective antiproliferative agents against prostate cancer cells

S Karmakar, H Kostrhunova, T Ctvrtlikova… - Journal of medicinal …, 2020 - ACS Publications
Herein, we describe the synthesis, characterization, and biological properties of Pt (IV)
derivatives of cisplatin with estramustine at the first axial position, which is known to disrupt …

Effects of phenylbutazone alone or in combination with a nutritional therapeutic on gastric ulcers, intestinal permeability, and fecal microbiota in horses

CM Whitfield‐Cargile, MC Coleman… - Journal of veterinary …, 2021 - Wiley Online Library
Background Gastrointestinal (GI) injury and dysbiosis are adverse events associated with
nonsteroidal anti‐inflammatory drug (NSAID) use in horses. Phenylbutazone has been …

[PDF][PDF] Characterization of garden cress mucilage and its prophylactic effect against indomethacin-induced enter-colitis in rats

EM Akl, FS Taha, SS Mohamed… - Biointerface Research in …, 2021 - academia.edu
The utilization of industrial waste such as oil industry waste in the production of natural
nutraceuticals is a very beneficial issue. So, the current study was established to assess the …

Suppression of β‐catenin signaling in colon carcinoma cells by a bacterial protein

A Nadeem, KM Aung, T Ray, A Alam… - … Journal of Cancer, 2021 - Wiley Online Library
Colorectal cancer is one of the leading causes of cancer‐related death worldwide. The
adenomatous polyposis coli (APC) gene is mutated in hereditary colorectal tumors and in …

Unveiling the interplay between NSAID-induced dysbiosis and autoimmune liver disease in children: insights into the hidden gateway to autism spectrum disorders …

DI Mohamed, HH Abo Nahas, AM Elshaer… - Frontiers in Cellular …, 2023 - frontiersin.org
Autism spectrum disorders (ASD) represent a diverse group of neuropsychiatric conditions,
and recent evidence has suggested a connection between ASD and microbial dysbiosis …