Rheumatoid arthritis: advances in treatment strategies

P Prasad, S Verma, Surbhi, NK Ganguly… - Molecular and cellular …, 2023 - Springer
Rheumatoid arthritis (RA) is characterised by severe joint and bone damage due to
heightened autoimmune response at the articular sites. Worldwide annual incidence and …

Focus on sex and gender: what we need to know in the management of rheumatoid arthritis

B Maranini, A Bortoluzzi, E Silvagni… - Journal of personalized …, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease, affecting mostly women with a
female/male ratio of 3: 1. It is characterized by symmetrical polyarthritis, leading to …

EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis

G Nagy, NMT Roodenrijs, PMJ Welsing… - Annals of the …, 2022 - ard.bmj.com
Objective To develop evidence-based European Alliance of Associations for Rheumatology
(EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid …

2022 EULAR recommendations for screening and prophylaxis of chronic and opportunistic infections in adults with autoimmune inflammatory rheumatic diseases

GE Fragoulis, E Nikiphorou, M Dey, SS Zhao… - Annals of the …, 2023 - ard.bmj.com
Objectives To develop EULAR recommendations for screening and prophylaxis of chronic
and opportunistic infections in patients with autoimmune inflammatory rheumatic diseases …

Host and bacterial factors linking periodontitis and rheumatoid arthritis

A Krutyhołowa, K Strzelec, A Dziedzic… - Frontiers in …, 2022 - frontiersin.org
Observations from numerous clinical, epidemiological and serological studies link
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …

The role of TNF-α and anti-TNF-α agents during preconception, pregnancy, and breastfeeding

K Romanowska-Próchnicka, A Felis-Giemza… - International journal of …, 2021 - mdpi.com
Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most
important inflammatory cytokines. In pregnancy, TNF-α influences hormone synthesis …

Secreted protein acidic and rich in cysteine mediated biomimetic delivery of methotrexate by albumin-based nanomedicines for rheumatoid arthritis therapy

L Liu, F Hu, H Wang, X Wu, AS Eltahan, S Stanford… - ACS …, 2019 - ACS Publications
Rheumatoid arthritis (RA) is one of the most common chronic autoimmune diseases. Despite
considerable advances in clinical treatment of RA, suboptimal response to therapy and …

The future of biosimilars: maximizing benefits across immune-mediated inflammatory diseases

HU Kim, R Alten, L Avedano, A Dignass, F Gomollón… - Drugs, 2020 - Springer
Biologics have transformed the treatment of immune-mediated inflammatory diseases such
as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Biosimilars—biologic …

Machine learning model for identifying important clinical features for predicting remission in patients with rheumatoid arthritis treated with biologics

BS Koo, S Eun, K Shin, H Yoon, C Hong… - Arthritis Research & …, 2021 - Springer
Background We developed a model to predict remissions in patients treated with biologic
disease-modifying anti-rheumatic drugs (bDMARDs) and to identify important clinical …

Exosomal microRNA-140-3p from human umbilical cord mesenchymal stem cells attenuates joint injury of rats with rheumatoid arthritis by silencing SGK1

Y Huang, L Chen, D Chen, P Fan, H Yu - Molecular Medicine, 2022 - Springer
Objective Over the years, microRNAs (miRNAs) have been involved in the pathogenesis of
rheumatoid arthritis (RA). We aim to investigate the role of human umbilical cord …