The preparation of both enantiomers of chiral molecules is among the most fundamental
tasks in organic synthesis, medicinal chemistry and materials science. Achieving this goal …

A protocol for the enantioselective synthesis of substituted vinylcyclopentanes has been
realised using cooperative palladium and isothiourea catalysis. Treatment of …

Axially chiral phenols are attractive targets in organic synthesis. This motif is central to many
natural products and widely used as precursors to, or directly, as chiral ligands and …

The development of methods for the selective acylative kinetic resolution (KR) of tertiary
alcohols is a recognised synthetic challenge with relatively few successful substrate classes …

A highly enantioselective isothiourea‐catalyzed acylative kinetic resolution (KR) of acyclic
tertiary alcohols has been developed. Selectivity factors of up to 200 were achieved for the …

Azole anions are highly competent in the activation of weak acyl donors, but, unlike neutral
(aprotic) Lewis bases, are not yet widely applied as acylation catalysts. Using a combination …

The use of chiral isothioureas to promote enantio‐and diastereoselective organocatalytic
transformations has rapidly developed in recent years. This chapter gives an overview of the …

The stereocontrol of tertiary alcohols represents a recurrent challenge in organic synthesis.
In the present paper, we describe a simple, efficient, and indirect method to …

Due to the omnipresence of chiral organofluorine compounds in pharmaceutical,
agrochemical, and material chemistry, the development of enantioselective methods for their …

The sequential acylative kinetic resolution (KR) of C2-symmetric (±)-1, 2-syn and (±)-1, 3-
anti-diols using a packed bed microreactor loaded with the polystyrene-supported …