Less than a century ago, gastric cancer was the most common cancer in the United States
and perhaps throughout the world. Despite its worldwide decline in incidence over the past …

The incidence and mortality of gastric cancer have fallen dramatically in US and elsewhere
over the past several decades. Nonetheless, gastric cancer remains a major public health …

Gastric cancer is a prevalent yet heterogeneous disease. From diet and lifestyle to genetics
and ethnicity, our appreciation of the complexity of gastric cancer has evolved. This review …

Gastric cancer is the second leading cause of cancer-related mortality and the fourth most
common cancer globally. There are, however, distinct differences in incidence rates in …

Diffuse-type gastric carcinoma (DGC) is characterized by a highly malignant phenotype with
prominent infiltration and stromal induction. We performed whole-exome sequencing on 30 …

While the incidence of gastric cancer has decreased worldwide in recent decades, the
incidence of signet-ring cell carcinoma (SRCC) is rising. SRCC has a specific epidemiology …

ContextHereditary diffuse gastric cancer is caused by germline mutations in the epithelial
cadherin (CDH1) gene and is characterized by an increased risk for diffuse gastric cancer …

Background and aims Clinicopathological characteristics of gastric cancer (GC) are
changing, especially in the West with a decreasing incidence of distal, intestinal-type …

Gastric cancer is classified into intestinal and diffuse types, the latter including a highly
malignant form, linitis plastica. A two-stage genome-wide association study (stage 1: 85,576 …

Objective: To test the hypothesis that signet ring cell (SRC) histology has a negative
prognostic value in patients with gastric adenocarcinoma (ADC). Summary Background …