A novel effect of Aprepitant: Protection for cisplatin-induced nephrotoxicity and hepatotoxicity

H Un, RA Ugan, D Kose, Y Bayir, E Cadirci… - European journal of …, 2020 - Elsevier
Cisplatin is widely used chemotherapeutic drug and have some serious side effects as
tissue toxicity and nausea and vomiting. Aprepitant is used in clinic as an anti-emetic drug …

[HTML][HTML] Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure …

EM Mantawy, RS Said, AK Abdel-Aziz - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Radiotherapy is one of the most relevant treatment modalities for various types of
malignancies. However, it causes premature ovarian failure (POF) and subsequent infertility …

The effect of rutin on ovarian ischemia-reperfusion injury in a rat model

C Nayki, U Nayki, F Keskin Cimen… - Gynecological …, 2018 - Taylor & Francis
The effect of rutin on ovarian ischemia-reperfusion (I/R) injury was investigated in this
experimental study. Eighteen Wistar albino female rats were divided into three groups as …

Protective effects of esculetin against ovary ischemia–reperfusion injury model in rats

M Güvenç, M Yüksel, T Kutlu, M Etyemez… - … of Biochemical and …, 2024 - Wiley Online Library
Aims Ovarian ischemia–reperfusion (I/R) injury is a phenomenon that necessitates urgent
intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young …

Protective effects of a natural product, paeoniflorin, on ischemia reperfusion injury on rat ovary tissue: histopathological, immunohistochemical, and biochemical study

P Bayram, SA Karamese, HS Erol… - Journal of …, 2023 - Taylor & Francis
In this study, the main hypothesis is that paeoniflorin may inhibit some cellular processes
such as oxidative stress and inflammation. For this reason, we aimed to investigate the …

Protective effect of pioglitazone on ovarian ischemia reperfusion injury of female rats via modulation of peroxisome proliferator activated receptor gamma and heme …

MMM Refaie, M El-Hussieny - International immunopharmacology, 2018 - Elsevier
Ovarian torsion is a dangerous gynecological emergency condition. Early diagnosis of this
case is necessary to preserve the function of the ovaries and fallopian tubes and prevent …

The protective effects of trimetazidine against ovary ischemia–reperfusion injury via the TLR4/Nf‐kB signal pathway

A Ozturk, A Topcu, E Deniz… - … of Biochemical and …, 2022 - Wiley Online Library
Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia,
irreversible damage to ovarian functions and infertility. In this process, there is no approved …

Evaluation of the protective effects of gossypin for ischemia/reperfusion injury in ovary tissue

B Dincer, I Cinar, M Yayla… - Journal of Obstetrics and …, 2022 - Wiley Online Library
Aim Ovarian ischemia–reperfusion (I/R) injury is a serious gynecological condition that
affects women of reproductive age and reduces ovarian reserve. Management of I/R injury …

Effects of Polygonum cognatum Meissn. extract on indomethacin induced gastric damage in rats

Y Bayir, N Tagiyeva, A Albayrak… - Biotechnic & …, 2023 - Taylor & Francis
We investigated the anti-ulcer activity of ethanol extracts of Polygonum cognatum on
indomethacin induced gastric damage in rats. We evaluated the number of ulcer areas …

Protective effects of nebivolol on ovarian ischemia–reperfusion injury in rat

S Colak, B Gurlek, A Topcu, L Tumkaya… - Journal of Obstetrics …, 2020 - Wiley Online Library
Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring
at rates of 2.7–7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) …