Hypertensive eye disease includes a spectrum of pathological changes, the most well
known being hypertensive retinopathy. Other commonly involved parts of the eye in …

Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes
mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that …

Antiaging therapies show promise in model organism research. Translation to humans is
needed to address the challenges of an aging global population. Interventions to slow …

With increase in life expectancy, the number of persons suffering from common age-related
brain diseases, including neurodegenerative (eg, dementia) and cerebrovascular (eg …

In ophthalmologic practice, retinal images are routinely obtained to diagnose and monitor
primary eye diseases and systemic conditions affecting the eye, such as diabetic …

Background Although cerebral small-vessel disease has been implicated in the
development of Alzheimer's disease (AD), the cerebral microcirculation is difficult to …

The retinal vasculature allows direct noninvasive visualization of the body's
mircrovasculature. Because the retina and other end organs (brain and kidney) share similar …

Background ageing is an important risk factor for a variety of human pathologies. Biological
age (BA) may better capture ageing-related physiological changes compared with …

The retinal vasculature provides a unique window to assess vascular health noninvasively
and directly in vivo. Advances in fundus photography and retinal image analysis techniques …

Microvascular dysfunction (MVD) is considered a crucial pathway in the development and
progression of cardiometabolic and renal disease and is associated with increased …