Distinguishing features of Long COVID identified through immune profiling
Post-acute infection syndromes may develop after acute viral disease. Infection with SARS-
CoV-2 can result in the development of a post-acute infection syndrome known as long …
CoV-2 can result in the development of a post-acute infection syndrome known as long …
Massively-multiplexed epitope map** techniques for viral antigen discovery
D Hu, AT Irving - Frontiers in Immunology, 2023 - frontiersin.org
Following viral infection, viral antigens bind specifically to receptors on the surface of
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …
Diagnostics and the neglected tropical diseases roadmap: setting the agenda for 2030
AA Souza, C Ducker, D Argaw, JD King… - Transactions of The …, 2021 - academic.oup.com
Accurate and reliable diagnostic tools are an essential requirement for neglected tropical
diseases (NTDs) programmes. However, the NTD community has historically underinvested …
diseases (NTDs) programmes. However, the NTD community has historically underinvested …
High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells
T follicular helper (TFH) cells are the conventional drivers of protective, germinal center (GC)–
based antiviral antibody responses. However, loss of TFH cells and GCs has been observed …
based antiviral antibody responses. However, loss of TFH cells and GCs has been observed …
High-resolution epitope map** and characterization of SARS-CoV-2 antibodies in large cohorts of subjects with COVID-19
Abstract As Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to
spread, characterization of its antibody epitopes, emerging strains, related coronaviruses …
spread, characterization of its antibody epitopes, emerging strains, related coronaviruses …
High-throughput identification of autoantibodies that target the human exoproteome
Autoantibodies that recognize extracellular proteins (the exoproteome) exert potent
biological effects but are challenging to detect. Here, we developed rapid extracellular …
biological effects but are challenging to detect. Here, we developed rapid extracellular …
Identification of highly conserved Trypanosoma cruzi antigens for the development of a universal serological diagnostic assay
Chagas Disease is an important neglected tropical disease caused by Trypanosoma cruzi.
There is no gold standard for diagnosis and commercial serological tests perform poorly in …
There is no gold standard for diagnosis and commercial serological tests perform poorly in …
[HTML][HTML] Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein
S Lapidus, F Liu, A Casanovas-Massana, Y Dai… - MedRxiv, 2021 - ncbi.nlm.nih.gov
Individuals with acute malaria infection generated high levels of antibodies that cross-react
with the SARS-CoV-2 Spike protein. Cross-reactive antibodies specifically recognized the …
with the SARS-CoV-2 Spike protein. Cross-reactive antibodies specifically recognized the …
Lack of association between pandemic chilblains and SARS-CoV-2 infection
An increased incidence of chilblains has been observed during the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic and attributed to viral infection. Direct …
syndrome coronavirus 2 (SARS-CoV-2) pandemic and attributed to viral infection. Direct …
[HTML][HTML] Phase Ib study of patients with metastatic castrate-resistant prostate cancer treated with different sequencing regimens of atezolizumab and sipuleucel-T
T Dorff, Y Hirasawa, J Acoba, I Pagano… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Combining an immune checkpoint inhibitor with a tumor vaccine may modulate
the immune system to leverage complementary mechanisms of action that lead to sustained …
the immune system to leverage complementary mechanisms of action that lead to sustained …