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Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
miRNA-based biomarkers, therapies, and resistance in Cancer
MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in size,
play important roles in gene regulation, and their dysregulation is implicated in human …
play important roles in gene regulation, and their dysregulation is implicated in human …
tRNA renovatio: rebirth through fragmentation
Summary tRNA function is based on unique structures that enable mRNA decoding using
anticodon trinucleotides. These structures interact with specific aminoacyl-tRNA synthetases …
anticodon trinucleotides. These structures interact with specific aminoacyl-tRNA synthetases …
Exploring the expanding universe of small RNAs
The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering
RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs …
RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs …
Emerging roles of tRNA-derived fragments in cancer
M Fu, J Gu, M Wang, J Zhang, Y Chen, P Jiang, T Zhu… - Molecular Cancer, 2023 - Springer
Abstract tRNA-derived fragments (tRFs) are an emerging category of small non-coding
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …
The role of non-coding RNAs in oncology
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications
Although high-throughput RNA sequencing (RNA-seq) has greatly advanced small non-
coding RNA (sncRNA) discovery, the currently widely used complementary DNA library …
coding RNA (sncRNA) discovery, the currently widely used complementary DNA library …
The life and times of a tRNA
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …
and insights in the last several years. We now have unprecedented knowledge of each step …
tRNA-derived small RNAs in human cancers: roles, mechanisms, and clinical application
M Zhou, X He, J Zhang, C Mei, B Zhong, C Ou - Molecular cancer, 2024 - Springer
Transfer RNA (tRNA)-derived small RNAs (tsRNAs) are a new type of non-coding RNAs
(ncRNAs) produced by the specific cleavage of precursor or mature tRNAs. tsRNAs are …
(ncRNAs) produced by the specific cleavage of precursor or mature tRNAs. tsRNAs are …
TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer
RNA modifications are important regulatory elements of RNA functions. However, most
genome-wide map** of RNA modifications has focused on messenger RNAs and transfer …
genome-wide map** of RNA modifications has focused on messenger RNAs and transfer …