The landscape of aging

Y Cai, W Song, J Li, Y **g, C Liang, L Zhang… - Science China Life …, 2022 - Springer
Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

[HTML][HTML] Sarcopenic obesity: emerging mechanisms and therapeutic potential

CL Axelrod, WS Dantas, JP Kirwan - Metabolism, 2023 - Elsevier
Sarcopenic obesity, or the loss of muscle mass and function associated with excess
adiposity, is a largely untreatable medical condition associated with diminished quality of life …

A wearable aptamer nanobiosensor for non-invasive female hormone monitoring

C Ye, M Wang, J Min, RY Tay, H Lukas… - Nature …, 2024 - nature.com
Personalized monitoring of female hormones (for example, oestradiol) is of great interest in
fertility and women's health. However, existing approaches usually require invasive blood …

Roles of estrogen, estrogen receptors, and estrogen-related receptors in skeletal muscle: regulation of mitochondrial function

K Yoh, K Ikeda, K Horie, S Inoue - International journal of molecular …, 2023 - mdpi.com
Estrogen is an essential sex steroid hormone that functions primarily in female reproductive
system, as well as in a variety of tissues and organs with pleiotropic effects, such as in …

The interplay between diabetes mellitus and menopause: clinical implications

I Lambrinoudaki, SA Paschou, E Armeni… - Nature Reviews …, 2022 - nature.com
The menopausal transition is an impactful period in women's lives, when the risk of
cardiovascular disease is accelerated. Similarly, diabetes mellitus profoundly impacts …

Sarcopenia in menopausal women: current perspectives

F Buckinx, M Aubertin-Leheudre - International Journal of Women's …, 2022 - Taylor & Francis
Menopause is associated with hormonal changes, which could accelerate or lead to
sarcopenia. Functional impairment and physical disability are the major consequences of …

The role of obesity in sarcopenia and the optimal body composition to prevent against sarcopenia and obesity

C Liu, KYK Cheng, X Tong, WH Cheung… - Frontiers in …, 2023 - frontiersin.org
Background Elderly people with low lean and high fat mass, are diagnosed with sarcopenic
obesity (SO), and often have poor clinical outcomes. This study aimed to explore the …

[HTML][HTML] Menopause—Biology, consequences, supportive care, and therapeutic options

SR Davis, JA Pinkerton, N Santoro, T Simoncini - Cell, 2023 - cell.com
Menopause is the cessation of ovarian function, with loss of reproductive hormone
production and irreversible loss of fertility. It is a natural part of reproductive aging. The …

Unraveling female reproductive senescence to enhance healthy longevity

L Dong, DBL Teh, BK Kennedy, Z Huang - Cell Research, 2023 - nature.com
In a society where women often want successful careers and equal opportunities to men, the
early nature of ovarian aging often forces women to make difficult life choices between …

Postmenopausal osteoporosis coexisting with sarcopenia: the role and mechanisms of estrogen

L Lu, L Tian - Journal of Endocrinology, 2023 - joe.bioscientifica.com
Estrogens (estradiol, estriol, and estrone) are important hormones that directly and indirectly
regulate the metabolism and function of bone and skeletal muscle via estrogen receptors …