Recent advances on CDK inhibitors: An insight by means of in silico methods
M Tutone, AM Almerico - European Journal of Medicinal Chemistry, 2017 - Elsevier
The cyclin dependent kinases (CDKs) are a small family of serine/threonine protein kinases
that can act as a potential therapeutic target in several proliferative diseases, including …
that can act as a potential therapeutic target in several proliferative diseases, including …
Discovery of Biphenyl–Sulfonamides as Novel β-N-Acetyl-d-Hexosaminidase Inhibitors via Structure-Based Virtual Screening
Novel insecticidal targets are always in demand due to the development of resistance. Of
Hex1, a β-N-acetyl-d-hexosaminidase identified in Ostrinia furnacalis (Asian corn borer), is …
Hex1, a β-N-acetyl-d-hexosaminidase identified in Ostrinia furnacalis (Asian corn borer), is …
Advancing DDoS Detection in 5GNetworks Through Machine Learningand Deep Learning Techniques
STR Bomidika - 2024 - diva-portal.org
This thesis explores the development and validation of advanced Machine Learning (ML)
and Deep Learning (DL) algorithms for detecting Distributed Denial of Service (DDoS) …
and Deep Learning (DL) algorithms for detecting Distributed Denial of Service (DDoS) …
Identification and preliminary SAR analysis of novel type-I inhibitors of TIE-2 via structure-based virtual screening and biological evaluation in in vitro models
Angiopoietin (ANG) ligands and their downstream TIE receptors have been validated as the
second vascular signaling system involving vessel remodeling and maturation. Among …
second vascular signaling system involving vessel remodeling and maturation. Among …
Analysis of next-generation sequencing data of miRNA for the prediction of breast cancer
Abstract Recently, Next-Generation Sequencing (NGS) has emerged as revolutionary
technique in the fields of '-omics' research. The Cancer Research Atlas (TCGA) is a great …
technique in the fields of '-omics' research. The Cancer Research Atlas (TCGA) is a great …
In Silico Exploration for Novel Type-I Inhibitors of Tie-2/TEK: The Performance of Different Selection Strategy in Selecting Virtual Screening Candidates
The receptor tyrosine kinase Tie-2 is involved in vessel remodeling and maturation, and has
been regarded as a potential target for the treatment of various solid tumors. The absence of …
been regarded as a potential target for the treatment of various solid tumors. The absence of …
Classify vertebrate hemoglobin proteins by incorporating the evolutionary information into the general PseAAC with the hybrid approach
SM Krishnan - Journal of theoretical biology, 2016 - Elsevier
Hemoglobin is an oxygen-binding protein widely present in all kingdoms of life from
prokaryotic to eukaryotic, but well established in the vertebrate system. An attempt was …
prokaryotic to eukaryotic, but well established in the vertebrate system. An attempt was …
Biomarker identification using Next Generation Sequencing data of RNA
Over the years, numerous studies have been performed in order to identify messenger
RNAs (mRNAs) that are differentially expressed at different biological conditions for various …
RNAs (mRNAs) that are differentially expressed at different biological conditions for various …
Identification of miRNA signature using next-generation sequencing data of prostate cancer
MicroRNAs (miRNAs) are a class of~ 22-nucleotide endogenous noncoding RNAs which
have critical functions across various biological processes. It is quite well-known that the …
have critical functions across various biological processes. It is quite well-known that the …
Integrated classifier: A tool for microarray analysis
Microarray technology has been developed and applied in different biological context,
especially for the purpose of monitoring the expression levels of thousands of genes …
especially for the purpose of monitoring the expression levels of thousands of genes …