Synthesizing biomaterials in living organisms
X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …
assembly process. The research on the mechanism of biomacromolecule formation also …
[HTML][HTML] How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?
Photodynamic therapy (PDT) is a promising method of tumor ablation and function-
preserving oncological intervention, which is minimally invasive, repeatable, and has …
preserving oncological intervention, which is minimally invasive, repeatable, and has …
Disulfidptosis classification of hepatocellular carcinoma reveals correlation with clinical prognosis and immune profile
T Wang, K Guo, D Zhang, H Wang, J Yin, H Cui… - International …, 2023 - Elsevier
A new mode of cell death, disulfidptosis, has been discovered. Clinical prognostic
significance of disulfidptosis related pattern in hepatocellular carcinoma (HCC). In this study …
significance of disulfidptosis related pattern in hepatocellular carcinoma (HCC). In this study …
Dual aggregations of a near-infrared aggregation-induced emission luminogen for enhanced imaging of Alzheimer's disease
Aggregation-induced emission (AIE) enables “Turn-On” imaging generally through single
aggregation of the AIE luminogen (AIEgen). Dual aggregrations of the AIEgen might further …
aggregation of the AIE luminogen (AIEgen). Dual aggregrations of the AIEgen might further …
Polymerization in living organisms
Vital biomacromolecules, such as RNA, DNA, polysaccharides and proteins, are
synthesized inside cells via the polymerization of small biomolecules to support and multiply …
synthesized inside cells via the polymerization of small biomolecules to support and multiply …
Supramolecular Senolytics via Intracellular Oligomerization of Peptides in Response to Elevated Reactive Oxygen Species Levels in Aging Cells
S Kim, JB Chae, D Kim, CW Park, Y Sim… - Journal of the …, 2023 - ACS Publications
Senolytics, which eliminate senescent cells from tissues, represent an emerging therapeutic
strategy for various age-related diseases. Most senolytics target antiapoptotic proteins …
strategy for various age-related diseases. Most senolytics target antiapoptotic proteins …
Tyrosinase‐Woven Melanin Nets for Melanoma Therapy through Targeted Mitochondrial Tethering and Enhanced Photothermal Treatment
M Tang, T Duan, Y Lu, J Liu, C Gao… - Advanced …, 2024 - Wiley Online Library
Manipulating intracellular biological processes and organelles has emerged as a pivotal
strategy to influence cellular physiological functions. Mitochondria, recognized as the …
strategy to influence cellular physiological functions. Mitochondria, recognized as the …
Mitochondria-Targeted Gold Biometallization for Photoacoustically Visualized Photothermal Cancer Therapy
Subcellular biomineralization systems with cellular intervention functions have shown great
potential in cancer theranostic applications. However, the lack of subcellular specificity, high …
potential in cancer theranostic applications. However, the lack of subcellular specificity, high …
Synthetic nanoassemblies for regulating organelles: from molecular design to precision therapeutics
Y Guo, P Li, X Guo, C Yao, D Yang - ACS nano, 2024 - ACS Publications
Each organelle referring to a complex multiorder architecture executes respective biological
processes via its distinct spatial organization and internal microenvironment. As the …
processes via its distinct spatial organization and internal microenvironment. As the …
Morphological Transformation and In Situ Polymerization of Caspase‐3 Responsive Diacetylene‐Containing Lipidated Peptide Amphiphile for Self‐Amplified …
In order to artificially regulate cell behaviors, intracellular polymerization as an emerging
chemical technique has attracted much attention. Yet, it is still a challenge to achieve …
chemical technique has attracted much attention. Yet, it is still a challenge to achieve …