[HTML][HTML] Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham… - Journal of controlled …, 2022 - Elsevier
The site-specific delivery of antitumor agents is of importance for providing effective cancer
suppression. Poor bioavailability of anticancer compounds and the presence of biological …

The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer

S Pordel, M Khorrami, F Saadatpour, D Rezaee… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …

[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy

H Liu, W Shen, W Liu, Z Yang, D Yin, C **ao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

microRNA-184 in the landscape of human malignancies: a review to roles and clinical significance

M Fattahi, D Rezaee, F Fakhari, S Najafi… - Cell Death …, 2023 - nature.com
MicroRNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) with a short length of 19–
22 nucleotides. miRNAs are posttranscriptional regulators of gene expression involved in …

Mechanisms and regulation of defensins in host defense

J Fu, X Zong, M **, J Min, F Wang… - Signal Transduction and …, 2023 - nature.com
As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Advancement of cell-penetrating peptides in combating triple-negative breast cancer

M Fatima, MAS Abourehab, G Aggarwal, GK Jain… - Drug Discovery …, 2022 - Elsevier
Extensive research efforts have been made and are still ongoing in the search for an ideal
anti-cancer therapy. Almost all chemotherapeutics require a carrier or vehicle, a drug …

Lights and shadows on the therapeutic use of antimicrobial peptides

D Bellotti, M Remelli - Molecules, 2022 - mdpi.com
The emergence of antimicrobial-resistant infections is still a major concern for public health
worldwide. The number of pathogenic microorganisms capable of resisting common …

[HTML][HTML] Bacteriocins in cancer treatment: Mechanisms and clinical potentials

Y Wang, Y Wang, T Sun, J Xu - Biomolecules, 2024 - mdpi.com
Cancer poses a severe threat to human health. Although conventional chemotherapy
remains a cornerstone of cancer treatment, its significant side effects and the growing issue …

Application of antimicrobial peptides as next-generation therapeutics in the biomedical world

M Datta, A Rajeev, I Chattopadhyay - Biotechnology and Genetic …, 2024 - Taylor & Francis
Antimicrobial peptide (AMP), also called host defense peptide, is a part of the innate immune
system in eukaryotic organisms. AMPs are also produced by prokaryotes in response to …

Current therapeutic approaches and promising perspectives of using bioengineered peptides in fighting chemoresistance in triple-negative breast cancer

M Azari, F Bahreini, VN Uversky, N Rezaei - Biochemical Pharmacology, 2023 - Elsevier
Breast cancer is a collation of malignancies that manifest in the mammary glands at the early
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …