P-Stereogenic phosphorus ligands in asymmetric catalysis

T Imamoto - Chemical reviews, 2024 - ACS Publications
Chiral phosphorus ligands play a crucial role in asymmetric catalysis for the efficient
synthesis of useful optically active compounds. They are largely categorized into two …

Recent advances in asymmetric borylation by transition metal catalysis

J Hu, M Ferger, Z Shi, TB Marder - Chemical Society Reviews, 2021 - pubs.rsc.org
Chiral organoboronates have played a critical role in organic chemistry and in the
development of materials science and pharmaceuticals. Much effort has been devoted to …

Recent strategies in the nucleophilic dearomatization of pyridines, quinolines, and isoquinolines

M Escolano, D Gaviña, G Alzuet-Piña… - Chemical …, 2024 - ACS Publications
Dearomatization reactions have become fundamental chemical transformations in organic
synthesis since they allow for the generation of three-dimensional complexity from two …

Progress in the Chemistry of Tetrahydroquinolines

I Muthukrishnan, V Sridharan, JC Menendez - Chemical reviews, 2019 - ACS Publications
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

Copper-boryl mediated organic synthesis

D Hemming, R Fritzemeier, SA Westcott… - Chemical Society …, 2018 - pubs.rsc.org
Organoboron compounds are valuable synthetic intermediates that find application in a
diverse variety of processes including both C–X and C–C bond-forming transformations …

Asymmetric synthesis of secondary and tertiary boronic esters

BSL Collins, CM Wilson, EL Myers… - Angewandte Chemie …, 2017 - Wiley Online Library
Non‐racemic chiral boronic esters are recognised as immensely valuable building blocks in
modern organic synthesis. Their stereospecific transformation into a variety of functional …

Rhodium-Catalyzed Double Hydroboration of Quinolines

R Wang, S Park - ACS Catalysis, 2023 - ACS Publications
Selective double hydroelementation of N-heteroarenes can be one of the most
straightforward and atom-economic routes toward dearomatized N-heterocycles bearing a …

Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity

Q Yang, Z Wang, CHH Hor, H **ao, Z Bian, J Wang - Science Advances, 2022 - science.org
Flavanols are privileged heterocyclic compounds in medicinal chemistry. It is notable to
develop an efficient and straightforward protocol for accessing chiral flavanols with precise …

Dearomative triple elementalization of quinolines driven by visible light

S Ishigaki, Y Nagashima, D Yukimori, J Tanaka… - Nature …, 2023 - nature.com
Organoboron and organosilicon compounds are used not only as synthetic building blocks
but also as functional materials and pharmaceuticals, and compounds with multiple boryl …

Enantiodivergent synthesis of chiral tetrahydroquinoline derivatives via Ir-catalyzed asymmetric hydrogenation: Solvent-dependent enantioselective control and …

Z Han, G Liu, X Yang, XQ Dong, X Zhang - ACS Catalysis, 2021 - ACS Publications
Ir-catalyzed asymmetric hydrogenation of quinolines was developed, and both enantiomers
of chiral tetrahydroquinoline derivatives could be easily obtained, respectively, in high yields …