The role of IgG Fc receptors in antibody-dependent enhancement

S Bournazos, A Gupta, JV Ravetch - Nature Reviews Immunology, 2020 - nature.com
Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of
certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non …

Learning from the past: development of safe and effective COVID-19 vaccines

S Su, L Du, S Jiang - Nature Reviews Microbiology, 2021 - nature.com
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
elicited an equally rapid response aiming to develop a COVID-19 vaccine. These efforts are …

Rapid COVID-19 vaccine development

BS Graham - Science, 2020 - science.org
Rapid development of a vaccine to prevent coronavirus disease 2019 (COVID-19) is a
global imperative, and defining the stakes and potential hurdles is critical because …

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

EA Kurt-Jones, L Popova, L Kwinn, LM Haynes… - Nature …, 2000 - nature.com
The innate immune system contributes to the earliest phase of the host defense against
foreign organisms and has both soluble and cellular pattern recognition receptors for …

Adjuvants for coronavirus vaccines

Z Liang, H Zhu, X Wang, B **g, Z Li, X ** vaccination strategies
M Trovato, R Sartorius, L D'Apice, R Manco… - Frontiers in …, 2020 - frontiersin.org
In the last decades, a number of infectious viruses have emerged from wildlife or re-
emerged, generating serious threats to the global health and to the economy worldwide …

Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans

PJ Klasse, DF Nixon, JP Moore - Science advances, 2021 - science.org
Multiple preventive vaccines are being developed to counter the coronavirus disease 2019
pandemic. The leading candidates have now been evaluated in nonhuman primates (NHPs) …