A scaffold protein manages the biosynthesis of steroidal defense metabolites in plants

M Boccia, D Kessler, W Seibt, V Grabe… - Science, 2024 - science.org
Solanaceae plants produce two major classes of valuable sterol-derived natural products—
steroidal glycoalkaloids and steroidal saponins—from a common cholesterol precursor …

Potato steroidal glycoalkaloids: properties, biosynthesis, regulation and genetic manipulation

Y Liu, X Liu, Y Li, Y Pei, A Jaleel, M Ren - Molecular Horticulture, 2024 - Springer
Steroidal glycoalkaloids (SGAs), predominantly comprising α-solanine (C45H73NO15) and
α-chaconine (C45H73NO14), function as natural phytotoxins within potatoes. In addition to …

From steroidal glycoalkaloids to steroidal saponins: Biosynthesis and ecological role in the Solanum genus

Y Li, J Luo - Molecular Plant, 2025 - cell.com
Solanaceae plants produce two major classes of valuable steroidal derived 10 specialized
metabolite-steroidal glycoalkaloids (SGAs) and steroidal 11 saponins (STSs)(Grzech et al …

[HTML][HTML] Key players in plant defense: How scaffold protein GAME15 orchestrates the biosynthesis of steroidal defense metabolite

S Kang, F Wang - Advanced Agrochem, 2024 - Elsevier
GAME15, a scaffold protein, orchestrates the biosynthesis of steroidal glycoalkaloids (a
class of compounds with known defensive properties) and steroidal saponins (which …

[HTML][HTML] Plants self-synthesize “agrochemical” to fight pests and diseases

X Yin, Y Li - Advanced Agrochem, 2024 - Elsevier
In this article, we present recent findings from a Nature Chemical Biology paper that
elucidate the mechanism of crucial biosynthetic steps involved in the synthesis of steroidal …