DNA is a highly charged polyelectrolyte and is prone to associative phase separation driven
by the presence of multivalent cations, charged surfactants, proteins, polymers and colloids …

Lung cancer is indeed a major cause of cancer‐related deaths worldwide. The development
of tumors involves a complex interplay of genetic, epigenetic, and environmental factors …

Highly disordered complexes between oppositely charged intrinsically disordered proteins
present a new paradigm of biomolecular interactions. Here, we investigate the driving forces …

The review begins with a concise description of the principles of phase separation. This is
followed by a comprehensive section on phase separation of chromatin, in which we recount …

Highly charged intrinsically disordered proteins are essential regulators of chromatin
structure and transcriptional activity. Here we identify a surprising mechanism of molecular …

Higher order folding of chromatin fibre is mediated by interactions of the histone H4 N-
terminal tail domains with neighbouring nucleosomes. Mechanistically, the H4 tails of one …

In this review, we highlight the recent progress in our understanding of the structure,
properties and applications of protein–polyelectrolyte complexes in both bulk and micellar …

Although numerous strategies are now available to generate rudimentary forms of synthetic
cell-like entities, minimal progress has been made in the sustained excitation of artificial …

Anionic polyelectrolyte filaments are common in biological cells. DNA, RNA, the cytoskeletal
filaments F-actin, microtubules, and intermediate filaments, and polysaccharides such as …

It is well known that chromatin structure is highly sensitive to the ionic environment.
However, the combined effects of a physiologically relevant mixed ionic environment of K+ …