Honokiol and its analogues as anticancer compounds: Current mechanistic insights and structure-activity relationship

P Prasher, R Fatima, M Sharma, B Tynybekov… - Chemico-biological …, 2023 - Elsevier
Lignans are plant-derived polyphenolic compounds with a plethora of biological
applications. Also, regarded as phytoestrogens, the lignans offer a variety of health benefits …

Nanotechnology-Based Drug Delivery Systems for Honokiol: Enhancing Therapeutic Potential and Overcoming Limitations

J Yang, J Shang, L Yang, D Wei, X Wang… - International journal …, 2023 - Taylor & Francis
Honokiol (HNK) is a small-molecule polyphenol that has garnered considerable attention
due to its diverse pharmacological properties, including antitumor, anti-inflammatory, anti …

[HTML][HTML] A novel combination therapy with Cabozantinib and Honokiol effectively inhibits c-Met-Nrf2-induced renal tumor growth through increased oxidative stress

L Rawat, M Balan, Y Sasamoto, A Sabarwal, S Pal - Redox biology, 2023 - Elsevier
Receptor tyrosine kinase (RTK), c-Met, is overexpressed and hyper active in renal cell
carcinoma (RCC). Most of the therapeutic agents mediate cancer cell death through …

Silk fibroin electrospun nanofiber blends with antibiotics and polyvinyl alcohol for burn wound healing

A Yerra, MM Dadala - Journal of Applied Polymer Science, 2022 - Wiley Online Library
Silk fibroin, is a structural and protein‐based biomacromolecule produced from Bombyx mori
silkworm. Silk fibroin has been widely being used for biomedical and biomaterial …

Honokiol-loaded PLGA-PEG nanoparticles with solubility in water for infusion treatment of solid cancer

DTT Le, NH Nguyen, HTM Do, CM Vu… - Journal of Drug Delivery …, 2025 - Elsevier
This study aimed to investigate honokiol-loaded PLGA-PEG nanoparticles with good stability
in water for infusion treatment. The characteristics of this nanoparticle-based delivery system …

Multiple Cell Cultures for MRI Analysis

Z Bober, D Aebisher, M Olek… - International Journal of …, 2022 - mdpi.com
Magnetic resonance imaging (MRI) is an imaging method that enables diagnostics. In recent
years, this technique has been widely used for research using cell cultures used in …

[HTML][HTML] Polymer-Free Electrospinning of β-Cyclodextrin–Oligolactide for Magnolol and Honokiol Pharmaceutical Formulations

DA Blaj, CA Peptu, M Balan-Porcarasu… - …, 2025 - pmc.ncbi.nlm.nih.gov
Background: Magnolol (MG) and honokiol (HK) are bioactive compounds extracted from
Magnolia obovata and Magnolia Officinalis trees with significant pharmacological properties …

Application of PLGA in Tumor Immunotherapy

J Wu, X Wang, Y Wang, Z Xun, S Li - Polymers, 2024 - mdpi.com
Biodegradable polymers have been extensively researched in the field of biomedicine.
Polylactic-co-glycolic acid (PLGA), a biodegradable polymer material, has been widely used …

Honokiol alleviates monosodium urate-induced gouty pain by inhibiting voltage-gated proton channels in mice

L Miao, Z Yuan, S Zhang, G Zhang - Inflammopharmacology, 2024 - Springer
Objective To investigate whether honokiol (HNK) acted as an analgesic in connection with
inhibiting the voltage-gated proton channel (Hv1). Methods The model of gouty arthritis was …

Regulation of the PTEN/PI3K/AKT pathway in RCC using the active compounds of natural products in vitro

X Wang, Z **e, Z Lou, Y Chen… - Molecular …, 2021 - spandidos-publications.com
Abstract Since Professor Tu Youyou won the 2015 Nobel Prize in Physiology and Medicine
for the discovery of artemisinin, which is used to treat malaria, increased attention has been …