The chemistry and biology of guanidine natural products

RGS Berlinck, S Romminger - Natural Product Reports, 2016 - pubs.rsc.org
Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …

A high-denticity chelator based on desferrioxamine for enhanced coordination of zirconium-89

EK Sarbisheh, AK Salih, SJ Raheem, JS Lewis… - Inorganic …, 2020 - ACS Publications
Herein we report a new high-denticity chelator based on the iron siderophore
desferrioxamine (DFO). Our new chelator—DFO2—is acyclic and was designed and …

Radiochemical, Computational, and Spectroscopic Evaluation of High-Denticity Desferrioxamine Derivatives DFO2 and DFO2p toward an Ideal Zirconium-89 Chelate …

E Khozeimeh Sarbisheh, KL Summers… - Inorganic …, 2023 - ACS Publications
Desferrioxamine (DFO) has long been considered the gold standard chelator for
incorporating [89Zr] Zr4+ in radiopharmaceuticals for positron emission tomography (PET) …

Successful Application of CuAAC Click Reaction in Constructing 64Cu-Labeled Antibody Conjugates for Immuno-PET Imaging

W Lee, S Sarkar, R Pal, JY Kim, H Park… - ACS Applied Bio …, 2021 - ACS Publications
Immuno-positron emission tomography (immuno-PET) is a rapidly growing imaging
technique in which antibodies are radiolabeled to monitor their in vivo behavior in real time …

Complexation of Ln3+ Ions with Cyclam Dipicolinates: A Small Bridge that Makes Huge Differences in Structure, Equilibrium, and Kinetic Properties

A Rodriguez-Rodriguez, M Regueiro-Figueroa… - Inorganic …, 2016 - ACS Publications
The coordination properties toward the lanthanide ions of two macrocyclic ligands based on
a cyclam platform containing picolinate pendant arms have been investigated. The synthesis …

High in Vivo Stability of 64Cu-Labeled Cross-Bridged Chelators Is a Crucial Factor in Improved Tumor Imaging of RGD Peptide Conjugates

S Sarkar, N Bhatt, YS Ha, PT Huynh… - Journal of Medicinal …, 2018 - ACS Publications
Although the importance of bifunctional chelators (BFCs) is well recognized, the
chemophysical parameters of chelators that govern the biological behavior of the …

Synthesis and Evaluation of New Generation Cross-Bridged Bifunctional Chelator for 64Cu Radiotracers

AV Dale, GI An, DN Pandya, YS Ha, N Bhatt… - Inorganic …, 2015 - ACS Publications
Bifunctional chelators have been successfully used to construct 64Cu-labeled
radiopharmaceuticals. Previously reported chelators with cross-bridged cyclam backbones …

Density functional theory study on the complexation of NOTA as a bifunctional chelator with radiometal ions

FY Adeowo, B Honarparvar… - The Journal of Physical …, 2017 - ACS Publications
1, 4, 7-Triazacyclononane-1, 4, 7-triacetic acid (NOTA) is a key bifunctional chelator utilized
for the complexation of metal ions in radiopharmaceutical applications; the ability of these …

Mono-and bis-alkylation of glyoxal-bridged tetraazamacrocycles using mechanochemistry

BH Abdulwahaab, BP Burke, J Domarkas… - The Journal of …, 2016 - ACS Publications
Glyoxal-bridged bisaminal tetraazamacrocyclic derivatives of 1, 4, 7, 10-
tetraazacyclododecane (cyclen) and 1, 4, 8, 11-tetraazacyclotetradecane (cyclam) can be N …

Improved light harvesting with graphene/boron nitride nano-heteroislands: a high-efficiency photosensitizer design

MA Al-Seady, HM Abduljalil, HH Abed… - Structural Chemistry, 2024 - Springer
Density function theory (DFT) and time-dependent density function theory (TD-DFT) are
used to deduce the structural, electronic, and optical characteristics of hexagonal boron …