Nanocarrier drug delivery systems: characterization, limitations, future perspectives and implementation of artificial intelligence
There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …
Drug delivery to the posterior segment of the eye: biopharmaceutic and pharmacokinetic considerations
R Varela-Fernández, V Díaz-Tomé… - Pharmaceutics, 2020 - mdpi.com
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …
[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …
because many diseases affect the retina and choroid leading to impaired vision or …
lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy
AA Thomas, S Biswas, B Feng, S Chen, J Gonder… - Diabetologia, 2019 - Springer
Aims/hypothesis The pathophysiology of diabetic retinopathy is linked to hyperglycaemia
and its effect on retinal microvascular tissues. The resulting endothelial injury changes the …
and its effect on retinal microvascular tissues. The resulting endothelial injury changes the …
Proteomic biomarkers of retinal inflammation in diabetic retinopathy
Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of
irreversible blindness in the developed world. DR arises as the result of prolonged …
irreversible blindness in the developed world. DR arises as the result of prolonged …
Pharmacokinetics of intravitreal anti-VEGF drugs in age-related macular degeneration
L García-Quintanilla, A Luaces-Rodríguez… - Pharmaceutics, 2019 - mdpi.com
Intravitreal administration of anti-vascular endothelial growth factor (VEGF) antibodies has
become the standard treatment for Age-Related Macular Degeneration; however, the …
become the standard treatment for Age-Related Macular Degeneration; however, the …
Human vitreous in proliferative diabetic retinopathy: characterization and translational implications
Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …
age population. DR is a progressive eye disease caused by long-term accumulation of …
[HTML][HTML] Angiogenic factors and cytokines in diabetic retinopathy
SF Abcouwer - Journal of clinical & cellular immunology, 2013 - ncbi.nlm.nih.gov
Diabetic retinopathy (DR) is a sight-threatening complication of both type-1 and type-2
diabetes. The recent success of treatments inhibiting the function of vascular endothelial …
diabetes. The recent success of treatments inhibiting the function of vascular endothelial …
Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …
indications, including neurodegenerative disorders. A broader understanding of the impact …
Proliferative vitreoretinopathy after eye injuries: an overexpression of growth factors and cytokines leading to a retinal keloid
F Morescalchi, S Duse, E Gambicorti… - Mediators of …, 2013 - Wiley Online Library
Eye injury is a significant disabling worldwide health problem. Proliferative Vitreoretinopathy
(PVR) is a common complication that develops in up to 40–60% of patients with an open …
(PVR) is a common complication that develops in up to 40–60% of patients with an open …