Tumor grading is a method to quantify the putative clinical aggressiveness of a neoplasm
based on specific histological features. A good grading system should be simple, easy to …

Pet dogs are becoming increasingly recognized as a population with the potential to inform
medical research through their treatment for a variety of maladies by veterinary health …

Species of Clostridium bacteria are notable for their ability to lyse tumor cells growing in
hypoxic environments. We show that an attenuated strain of Clostridium novyi (C. novyi-NT) …

Mesenchymal tumors include those tumors arising from the supporting mesenchymal tissues
of the dermis and subcutis (fibrous connective tissue, blood vessels, lymphatics, nerves …

Genomic and precision medicine research has afforded notable advances in human cancer
treatment, yet applicability to other species remains uncertain. Through whole-exome and …

Soft tissue sarcomas are a heterogeneous population of mesenchymal tumors that constitute
15% and 7% of all skin and subcutaneous tumors in the dog and cat, respectively. 1 The …

Standardization of tumor assessment lays the foundation for validation of grading systems,
permits reproducibility of oncologic studies among investigators, and increases confidence …

Soft tissue sarcomas are derived from tissues of mesenchymal origin. Although local
recurrence following surgical resection is the characteristic challenge in their management …

Mitotic count (MC) is an important element for grading canine cutaneous mast cell tumors
(ccMCTs) and is determined in 10 consecutive high-power fields with the highest mitotic …

Objective To determine outcome of dogs with a diagnosis of soft tissue sarcoma managed in
first opinion practice. Study Design Retrospective, case‐controlled study Animals Dogs (n …