Metabolic reprogramming is a key alteration in tumorigenesis. In cancer cells, changes in
metabolic fluxes are required to cope with large demands on ATP, NADPH, and NADH, as …

Brain tumors represent some of the most aggressive malignancies. The latest WHO
Classification of Tumors of the Central Nervous System recognizes more than 100 primary …

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and
clinically heterogenous. The application of omics technologies—mainly studying nucleic …

Background Acute myeloid leukemia (AML) is a highly aggressive hematological
malignancy characterized by extensive genetic abnormalities that might affect the prognosis …

Molecular groups of medulloblastoma (MB) are well established. Novel risk stratification
parameters include Group 3/4 (non-WNT/non-SHH) methylation subgroups I–VIII or whole …

Medulloblastoma (MB), one of the most common malignant pediatric brain tumor, is a
heterogenous disease comprised of four distinct molecular groups (WNT, SHH, Group 3 …

Medulloblastomas (MB) molecularly designated as Group 3 (Grp 3) MB represent a more
clinically aggressive tumor variant which, as a group, displays heterogeneous molecular …

Background. Basal‐like breast cancer (BLBC) exhibits worse pathological features than
other breast cancer subtypes, and patients diagnosed with BLBC have short disease‐free …

Medulloblastoma (MB) is the most common malignant brain tumor in childhood and is
stratified into four molecular groups‒WNT, SHH, Group 3 and Group 4. Group 3 MB patients …

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and
clinically very heterogenous. To unravel phenotypically relevant MB subtypes, we compiled …