Betulin and betulinic acid: Triterpenoids derivatives with a powerful biological potential

A Hordyjewska, A Ostapiuk, A Horecka… - Phytochemistry …, 2019 - Springer
Betulin, a pentacyclic triterpene and a plant pentacyclic triterpene metabolite, can be found
in large quantities in the outer bark of the birches (Betula, Betulaceae). Betulinic acid …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - Elsevier
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

[HTML][HTML] Vanillin: A food additive with multiple biological activities

A Olatunde, A Mohammed, MA Ibrahim… - European Journal of …, 2022 - Elsevier
Abstract Vanillin (4-hydroxy-3-methoxybenzaldehyde) is a known natural aromatic
flavouring agent and the major component of vanilla extracted from cured vanilla pods …

Evaluation of antioxidant activity of vanillin by using multiple antioxidant assays

A Tai, T Sawano, F Yazama, H Ito - Biochimica et Biophysica Acta (BBA) …, 2011 - Elsevier
BACKGROUND: Vanillin, a compound widely used in foods, beverages, cosmetics and
drugs, has been reported to exhibit multifunctional effects such as antimutagenic …

[HTML][HTML] Is everything we eat associated with cancer? A systematic cookbook review

JD Schoenfeld, JPA Ioannidis - The American journal of clinical nutrition, 2013 - Elsevier
Background: Nutritional epidemiology is a highly prolific field. Debates on associations of
nutrients with disease risk are common in the literature and attract attention in public media …

Polyphenols in colorectal cancer: current state of knowledge including clinical trials and molecular mechanism of action

MN Alam, M Almoyad, F Huq - BioMed research international, 2018 - Wiley Online Library
Polyphenols have been reported to have wide spectrum of biological activities including
major impact on initiation, promotion, and progression of cancer by modulating different …

Overview of the role of vanillin on redox status and cancer development

DP Bezerra, AKN Soares… - Oxidative medicine and …, 2016 - Wiley Online Library
Bioactive natural products play critical roles in modern drug development, especially
anticancer agents. It has been widely reported that various pharmacological activities of …

Cytotoxic and apoptotic effects of six herbal plants against the human hepatocarcinoma (HepG2) cell line

S Machana, N Weerapreeyakul, S Barusrux… - Chinese medicine, 2011 - Springer
Abstract Background Six plants from Thailand were evaluated for their cytotoxicity and
apoptosis induction in human hepatocarcinoma (HepG2) as compared to normal African …

[HTML][HTML] Potential effects of phenolic compounds that can be found in olive oil on wound healing

L Melguizo-Rodríguez, E de Luna-Bertos… - Foods, 2021 - mdpi.com
The treatment of tissue damage produced by physical, chemical, or mechanical agents
involves considerable direct and indirect costs to health care systems. Wound healing …

Pro-oxidant natural products as anticancer agents

C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - benthamdirect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …