Incidence and prevalence of multiple sclerosis in Europe: a systematic review

E Kingwell, JJ Marriott, N Jetté, T Pringsheim… - BMC neurology, 2013‏ - Springer
Background Multiple sclerosis (MS) is the most common cause of neurological disability in
young adults worldwide and approximately half of those affected are in Europe. The …

Multiple sclerosis: current knowledge and future outlook

CP Kamm, BM Uitdehaag, CH Polman - European neurology, 2014‏ - karger.com
Background: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous
system characterized by demyelination and axonal loss. The etiology of MS is unknown; …

Epidemiology of multiple sclerosis

E Leray, T Moreau, A Fromont, G Edan - Revue neurologique, 2016‏ - Elsevier
Multiple sclerosis (MS) is the most frequently seen demyelinating disease, with a prevalence
that varies considerably, from high levels in North America and Europe (> 100/100,000 …

Modeling multiple sclerosis using mobile and wearable sensor data

S Gashi, P Oldrati, M Moebus, M Hilty, L Barrios… - npj Digital …, 2024‏ - nature.com
Multiple sclerosis (MS) is a neurological disease of the central nervous system that is the
leading cause of non-traumatic disability in young adults. Clinical laboratory tests and …

Obesity and multiple sclerosis: a mendelian randomization study

LE Mokry, S Ross, NJ Timpson, S Sawcer… - PLoS …, 2016‏ - journals.plos.org
Background Observational studies have reported an association between obesity, as
measured by elevated body mass index (BMI), in early adulthood and risk of multiple …

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

P Connick, M Kolappan, C Crawley… - The Lancet …, 2012‏ - thelancet.com
Background More than half of patients with multiple sclerosis have progressive disease
characterised by accumulating disability. The absence of treatments for progressive multiple …

Multiple sclerosis: geoepidemiology, genetics and the environment

R Milo, E Kahana - Autoimmunity reviews, 2010‏ - Elsevier
Multiple sclerosis (MS) is a chronic immune-mediated demyelinating disease of the central
nervous system characterized by relapses and remissions. The risk of acquiring this …

Vitamin D and multiple sclerosis

A Ascherio, KL Munger, KC Simon - The Lancet Neurology, 2010‏ - thelancet.com
The hypothesis that adequate vitamin D nutrition can contribute to the prevention of multiple
sclerosis (MS) was originally proposed to explain the geographical distribution of MS, but …

Temporal trends in the incidence of multiple sclerosis: a systematic review

A Alonso, MA Hernán - Neurology, 2008‏ - neurology.org
Background: Multiple sclerosis (MS) has been traditionally considered to be more frequent
in women and in regions more distant from the equator. However, recent reports suggest …

Environmental factors and multiple sclerosis

GC Ebers - The Lancet Neurology, 2008‏ - thelancet.com
Studies in Canada have provided strong evidence that environmental factors act at a
population level to influence the unusual geographical distribution of multiple sclerosis (MS) …